ID   A0A2U1LJ43_ARTAN        Unreviewed;       873 AA.
AC   A0A2U1LJ43;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=ATP-NAD kinase-like domain-containing protein {ECO:0000313|EMBL:PWA49018.1};
GN   ORFNames=CTI12_AA485630 {ECO:0000313|EMBL:PWA49018.1};
OS   Artemisia annua (Sweet wormwood).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC   Artemisiinae; Artemisia.
OX   NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA49018.1, ECO:0000313|Proteomes:UP000245207};
RN   [1] {ECO:0000313|EMBL:PWA49018.1, ECO:0000313|Proteomes:UP000245207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC   TISSUE=Leaf {ECO:0000313|EMBL:PWA49018.1};
RX   PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA   Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA   Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA   Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT   "The genome of Artemisia annua provides insight into the evolution of
RT   Asteraceae family and artemisinin biosynthesis.";
RL   Mol. Plant 11:776-788(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWA49018.1}.
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DR   EMBL; PKPP01009113; PWA49018.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U1LJ43; -.
DR   Proteomes; UP000245207; Unassembled WGS sequence.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0019674; P:NAD metabolic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR   InterPro; IPR017438; ATP-NAD_kinase_N.
DR   InterPro; IPR017437; ATP-NAD_kinase_PpnK-typ_C.
DR   InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   PANTHER; PTHR20275; NAD KINASE; 1.
DR   PANTHER; PTHR20275:SF0; NAD KINASE; 1.
DR   Pfam; PF20143; NAD_kinase_C; 1.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR   SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:PWA49018.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245207};
KW   Transferase {ECO:0000313|EMBL:PWA49018.1}.
FT   REGION          485..586
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        492..546
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        555..581
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   873 AA;  97836 MW;  00EAD6E4426688AF CRC64;
     MTSSCHSVIV VDMNRASLIP KPYTFDMNHR FRDSNNNNKL PQRRRISVAA AAAAGAEVTN
     PFSVSIGLDS QTYQSHNLTQ LPWVGPLPGD IAEVEAYCRI FRAAERLHNA LMDTLCNPLT
     GECSVSYAFP SEDKPLLEDK IVSVLGCMIC LLNKGREDLL SGRSTIMKSF SVSDVDIMED
     KLPPLAIFRR EMKRYCESLH VALEIFLTAD DSRSLDVWRK LQRLKNVCYD SGLPRGDDYP
     PHSLFANWNP VYLSTSKEDI EPTDSEVAFW RGSQLTEESL KWLIEKGFKT IVDLRAESVN
     DVFYEAALQD AVSSGKIELV RIPVEVGTAP SMAQVELFLT VISDSKKKPI YLHSKEGVWR
     TSAMVSRWRQ QMSRYGSPSN VQARDKMSKE QNSKVAIEEE ENIAEFSTTT NDKISNGAYK
     GADTSVLDET GDDQDGVVFD FRVNPIESQL PPSNVFSRKE MSIFFKNKTL SPTSYFTFER
     KRLEKQTKSR KKQNYNGSYL SINNPDSEYV EMGSPNGSAT NGSLATYSEN SASQNHNNSL
     PSRSSLEEFS DADRQATSEV SARVTGTDVV AEKSSNGKAV RSSGNEDEEL IEGNMCASTT
     GVVRVQSRKK AEMFLVRTDG FSCTREKVTE SSLAFTHPST QQQMLMWKSS PKTVLLLKKL
     GLELMEQAKE YLLCETQAAS YLYHQENMNV LVEPEVHDIF ARIPGFGFVQ TFYSQDTRFL
     VEQFEDFKQD LKRVIHGNNT LEGVYITLRM RLRCEIFRNG KAMPGKVFDV LNEVVVDRGS
     NPYLSKIECY EHDRLITKVQ GDGVIVATPT GSTAYSTAAG GSMVHPNVPC MLFTPICPHS
     LSFRPVILPD SARLELKVRQ LSCANASSQF KYL
//