ID A0A2U1LTI2_ARTAN Unreviewed; 505 AA.
AC A0A2U1LTI2;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Transcription factor {ECO:0000256|RuleBase:RU369104};
DE Short=bHLH transcription factor {ECO:0000256|RuleBase:RU369104};
DE AltName: Full=Basic helix-loop-helix protein {ECO:0000256|RuleBase:RU369104};
GN ORFNames=CTI12_AA445980 {ECO:0000313|EMBL:PWA52316.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA52316.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA52316.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA52316.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU369104}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA52316.1}.
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DR EMBL; PKPP01007831; PWA52316.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1LTI2; -.
DR STRING; 35608.A0A2U1LTI2; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd11449; bHLH_AtAIB_like; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR045084; AIB/MYC-like.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR025610; MYC/MYB_N.
DR PANTHER; PTHR11514; MYC; 1.
DR PANTHER; PTHR11514:SF47; TRANSCRIPTION FACTOR BHLH13; 1.
DR Pfam; PF14215; bHLH-MYC_N; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU369104};
KW Reference proteome {ECO:0000313|Proteomes:UP000245207};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU369104};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU369104}.
FT DOMAIN 355..404
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT REGION 341..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 505 AA; 56699 MW; 46EF6520B73E0087 CRC64;
MKSEASMVIG EENLSEEDKS IISSVLGSKA FNYLLSASFA NECSFTSLAN DENLQHKLSH
LVDNPNSARF SWNYAIFWQV SRSKSGELVL GWGDGSCREP KEGEEFDIGR ILRFRLENDE
KQQMMKKNVL QKVHGLFGGL DEDNYAYGLD KVTDTEMFFL LSMYFLFRNG EGGPGRCFGQ
GRDVWISDAL SSGSDYCFRS NLAKAAGIQT VVMVPTDIGV LEVGSVRSIP ENPGVLQSIR
ASFSGNCVAN GYGHPDRVIS TIKMSKIFGQ DFSSGMNQPQ FREKIAVRKP EEPARVPFSN
WAKIPGPQLQ IDFTGITESK VSDECLVRDD REMVTTIIDE KRPRKRGRKP ANGREEPLNH
VEAERQRREK LNQRFYALRA VVPNISKMDK ASLLGDAITY ITDLQKKLKE MESERQSPNY
KVSLEKIEVQ ATENEVLVRV TSPLEAHPVS KVIQTFEESK IKVVESKMNA INDLVFHTFV
VKSQGPEQLT KESLISAFSR ETSSS
//
