ID A0A2U1M3C3_ARTAN Unreviewed; 1531 AA.
AC A0A2U1M3C3;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=UvrD-like Helicase, ATP-binding domain, P-loop containing nucleoside triphosphate hydrolase {ECO:0000313|EMBL:PWA55756.1};
GN ORFNames=CTI12_AA426770 {ECO:0000313|EMBL:PWA55756.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA55756.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA55756.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA55756.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA55756.1}.
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DR EMBL; PKPP01006673; PWA55756.1; -; Genomic_DNA.
DR STRING; 35608.A0A2U1M3C3; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR039904; TRANK1.
DR PANTHER; PTHR21529; MAMMARY TURMOR VIRUS RECEPTOR HOMOLOG 1, 2 MTVR1, 2; 1.
DR PANTHER; PTHR21529:SF4; TPR AND ANKYRIN REPEAT-CONTAINING PROTEIN 1; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:PWA55756.1};
KW Helicase {ECO:0000313|EMBL:PWA55756.1};
KW Hydrolase {ECO:0000313|EMBL:PWA55756.1};
KW Nucleotide-binding {ECO:0000313|EMBL:PWA55756.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000245207}.
FT DOMAIN 79..153
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 198..333
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT REGION 1444..1531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1445..1460
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1493..1507
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1515..1531
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1531 AA; 174128 MW; 187EF1D5A430F3CF CRC64;
MGERNFQNMI SLLDNLRLFE SLLFQENLVS DELEDLLTSK PLQDDGNTSS INYIRATCLS
VLRSLQISLE GLSLPDVRDE RALMNFCFEN ASLIFCTTSS SYKLHRIKME PLNILVIDEA
AQLKEAESTI PLQLPGMKHA ILIGDECQLP AMLYFDGQNA CGQVCIESGF GRSLFERLSA
LANPKHLLNV QYLPGPMFGP YSFINVVGGR EEKDDDDRSW RNLVEVAVVM KIVQNVYKAG
NVSKEKLTIG VVSTYSAQVV SIQEKLAHKY EKLDGFSVRV KSIDGFQGGE EDIIILSTVR
SNSRGSVGFI SSPQRTNVAL TRARHCLWIL GNERTLLNSE SVWTDLVHDA RNRHSLFDAD
SDDSLKMTII AAKKELEQLD DLVNGNSVLF SDDFRRSFGK LTCARLKKLV LNLLLKLSGG
WQPKSRSEGE CMQVMKVWDI LTFEEIPKLT KRLESIFAAY TDNYINRCTA KCLEGNLEVP
RCWPPSQEVI RFRIYEPESS EIRDVEPDDV PENRNPSVLR QLFVTVSPRL CHAVKQHVSH
LTSSSIDINL DDVDVTSDFS DVPDTFCEVP IKNYPLVITF HKFLMMLDST LGNSFFGRFR
EAREGSHAQT IARGIDFRFQ DIRSLFYKEF LSNRTSGKQE KGLVSEIFQL KQNFRTHAGV
LDLTESVIEI LYCYFVHSMD ILEPETSLIS GEAPVLLESG NDENAIVTIF GDTGTSGEIV
ILVRDDCAKA EICDYIGKNA LVLTIVECKG LEFQDVLLYN FFGTSPLKDQ WRVIYGYMKD
HDWLDEKYPQ SFPPFKEAKH SVLCSELKQL YVAITRTRQR LWICENQEEL SKPMFDYRKM
RGLVQVRKLD DSVAQAMRVA SSPQEWRERG KKLFYENNFV MATMCFERAG DTIWEKLAKA
SGLRASAEQI RGTNHEAFQS YVREAAGIFE SIGKLEPAAS CYCDLAEYER AGKIYLYKCG
KMDAAAECFT LAGCYSDAAE AYAKGDKLSN CLSDDNLPSK EIEQIEQEFL ESCALDYHGH
KDLKSMMKFV RAFFSMESKR LFLRSLGCLD ELLLLEEESG HFFEAAELAR SWGNVLREAD
LMEKAGDIKE ATALLLWYVF LKLLWGNGNR CWPLKQFDQK EELSSKVKSL AELDSEFYYD
FVCSELKVIS GQCSTLPELK EDLHAYQKSG SLKGKYLSIR KLLDAHFQQH FSKYEWEDEL
PIGINEHCDK IFENKVSVRT LVFYWKLWKE NVVEIFESLG TFDNEEPNKL KGPIDFSLMY
FGVRKQHVKG NMVYLLVDED AEWVRNYGQK GLLKVKKRVI IDGRQLVIAI RSYWQSELFS
VGIKVLEVLE GLRKSKSSGS AFHQSTSLLH LFEVSRSLLD CQYLNLTNSD TRKLQRFLGI
SLTLVQIALC ELRSLSNLFA ASRQEAEIPD IMKRMEVAID WLQSNRPKID DFLKRYAMSQ
ESKAVQMVVP ESSITTQVEE TGDKKNQDEE TGDALQVEPM LEKQTSGGNT QDAKNKKGKD
DNTKGDNNKG NNNKGKNSKG KKGKKGKGKK K
//
