ID A0A2U1NGE3_ARTAN Unreviewed; 773 AA.
AC A0A2U1NGE3;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 22-FEB-2023, entry version 14.
DE SubName: Full=ARF-GAP domain 4 {ECO:0000313|EMBL:PWA72592.1};
GN ORFNames=CTI12_AA269170 {ECO:0000313|EMBL:PWA72592.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA72592.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA72592.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA72592.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA72592.1}.
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DR EMBL; PKPP01002874; PWA72592.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1NGE3; -.
DR STRING; 35608.A0A2U1NGE3; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08204; ArfGap; 1.
DR CDD; cd07606; BAR_SFC_plant; 1.
DR CDD; cd13250; PH_ACAP; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR045258; ACAP1/2/3-like.
DR InterPro; IPR035670; AGD1/2/3/4_BAR_plant.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR23180:SF244; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD2; 1.
DR PANTHER; PTHR23180; CENTAURIN/ARF; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01412; ArfGap; 1.
DR Pfam; PF16746; BAR_3; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00105; ArfGap; 1.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000245207};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 2..226
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 288..422
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 471..603
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REPEAT 680..712
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 713..745
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 773 AA; 87127 MW; 93770485A44AB57B CRC64;
MTAFIKLDDS PMFHKQVRYL EQTTDELKTR CQKLHKGSKK YMDGLGEACN MDYIFADALE
AFGGGQDDPT SVSIGGPIMS KFVSAFREIE TFKELLRSQV EHLLVDRLSQ FLAEDLQDTK
ESRKRFDKAA SAYDQAREKV ASLKKSTRDE VVAELEEDLQ NSKSAFERSR FNLVNSLMNI
EAKKKYTFLE SISAIMDAHL RYFKLGYELL SQMEPFIHQV LTYAQQSKEQ ASIEHDRLAK
RIQEFRTQAE MKEAVPSNVG HVNVNGVGMS SDKDIDAIMQ STTKGTVQTI KQGYLLKRSS
SLRADWKRRF FVLDSRGNLY YHRILPNKPV GTQSTNSLQS TEQQSRVFGR FRSRHSRAAS
HDDDNLECHT VDLRTSTIKA DAEDSDLRLC FRIISPMKTY TLQAENEGER IDWMNKITGV
IASLLNSHLK QTHFNRSNLR STLESVGEDF DASEADNVGS TLDNMNINSA DSVSSILREI
PGNDLCAECG AREPDWASLN LGILMCIECS GVHRNLGVHI SKVRSITLDV KVWEPTVMDL
FRNLGNTFCN SIWENLLQAD SKEGSNAFAV SKPSPGDAFQ QREKYIISKY VEKRLMSREE
TSTTTPSHAT RIWESVKCND IREVYRLIAT SNTNIVNTTY NEVADADLFH NVHEHDLAEK
NGPLSCKKIK NPSKPDSCLT GCTLLHLACN SGYQVMLELL LQFGADINKC DYHGRTPLHH
CIFSGNNKLA KYMLRRGAVG SIKDGGGRSA LERAMEMGAI TDDELLILLS EGK
//
