ID A0A2U1NH81_ARTAN Unreviewed; 840 AA.
AC A0A2U1NH81;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=AB-hydrolase lipase domain, Alpha/Beta hydrolase fold protein {ECO:0000313|EMBL:PWA72874.1};
GN ORFNames=CTI12_AA266090 {ECO:0000313|EMBL:PWA72874.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA72874.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA72874.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA72874.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL8 family.
CC {ECO:0000256|ARBA:ARBA00007337}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA72874.1}.
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DR EMBL; PKPP01002828; PWA72874.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1NH81; -.
DR STRING; 35608.A0A2U1NH81; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:InterPro.
DR Gene3D; 3.30.1330.30; -; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR006693; AB_hydrolase_lipase.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR001921; Ribosomal_eL8.
DR InterPro; IPR004037; Ribosomal_eL8-like_CS.
DR InterPro; IPR004038; Ribosomal_eL8/eL30/eS12/Gad45.
DR InterPro; IPR018492; Ribosomal_eL8/Nhp2.
DR PANTHER; PTHR11005:SF135; AB-HYDROLASE LIPASE DOMAIN, ALPHA_BETA HYDROLASE FOLD PROTEIN-RELATED; 1.
DR PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR Pfam; PF04083; Abhydro_lipase; 1.
DR Pfam; PF01248; Ribosomal_L7Ae; 1.
DR PRINTS; PR00881; L7ARS6FAMILY.
DR PRINTS; PR00882; RIBOSOMALL7A.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF55315; L30e-like; 1.
DR PROSITE; PS01082; RIBOSOMAL_L7AE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:PWA72874.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000245207};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 270..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 51..140
FT /note="Ribosomal protein eL8/eL30/eS12/Gadd45"
FT /evidence="ECO:0000259|Pfam:PF01248"
FT DOMAIN 425..472
FT /note="Partial AB-hydrolase lipase"
FT /evidence="ECO:0000259|Pfam:PF04083"
SQ SEQUENCE 840 AA; 95198 MW; 19653DEE10134A9D CRC64;
MATSCEDSEE EEDPQAAFEA TTLFKMLLKY RPEDKATKKE RLVKRAQAES EGKTVEAKKP
IVVKYGLNHI TYLIEQNKAQ LVIIAHDVDP IELVVWLPAL CRKMEIPYCI VKGKSRLGTI
VHQKTAAALC LTTVKNEDKM EFSRVLEAIK TITYESLSNI LRLINGISAL LLRMLPGKAG
MLEGMSGWEL RPVLRGPRFP RWMEDGVSSF NHFVHELSTN YDPTSAVDYT SGDEIDEFED
ASTYPASPLT PGLKFSRAAS FKRERRHRHW IISVIKFLFL PARLMLVIPL YVLKKIIRRG
IKALHTTNQK RTGSSNTTKK ALDHVVQRAT DRRRGLIEDL HLGIEIVIET IFDVIHYAAR
CLISPLDTLR SLLRWSSSPS GTRKSDNNDS DAIVATATLA NPDPTPAERK SNLSKRLNTD
ARTCKDVITE LGYPYEAINV VTSDGYVLLL ERIPRRDSKK AVYLQHGVFD SSMCIYFHLS
IMVSVFFTSW VSNGIVGSPA FAAYDHGYDV FLGNFRGLVS REHVDKKISS RQYWRYSINE
HGTKDLPALI EKINEVKTSE LKSTSESSTN EESNNEQPYK LCAICHSLGG AAILMYIITR
RVEKIPHRLS RSIMLSPAGF HHDSPFFFTV IEYTCLWLSP IIAPIFPGLY IPTRFFRMLV
NKLARDLTNY PAVGGLVQTL MSYIVGGDCS NWVGVMGLPH YNMNDMPGVS FGVARHLAQI
KRSARFRMFD YGSPEANRNV YGSPEPLDLG ELYNLIDVPV DLVAGMKDKV ILPSMIRKHY
RLMKEGGVRA SYKEFEYAHL DFTFSHRAEL LEYVMSRLLQ VDTKHRSLKL KNKEEILALK
//
