ID A0A2U1NMX4_ARTAN Unreviewed; 381 AA.
AC A0A2U1NMX4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=Reverse transcriptase zinc-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CTI12_AA246610 {ECO:0000313|EMBL:PWA74859.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA74859.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA74859.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA74859.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA74859.1}.
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DR EMBL; PKPP01002500; PWA74859.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1NMX4; -.
DR STRING; 35608.A0A2U1NMX4; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR026960; RVT-Znf.
DR PANTHER; PTHR46736:SF105; POLYNUCLEOTIDYL TRANSFERASE, RIBONUCLEASE H FOLD; 1.
DR PANTHER; PTHR46736; ZF-RVT DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13456; RVT_3; 1.
DR Pfam; PF13966; zf-RVT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000245207}.
FT DOMAIN 134..228
FT /note="Reverse transcriptase zinc-binding"
FT /evidence="ECO:0000259|Pfam:PF13966"
FT DOMAIN 333..381
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|Pfam:PF13456"
SQ SEQUENCE 381 AA; 43217 MW; 4BD1F569877207B0 CRC64;
MEDSLPARIL KTRYYPRGSF LDARIGYRPS FVWRSLCTAR DIIRKGKRWN IGNGMKVRIW
EDYWLEGFRT LDYRPENSDY RVVNDLLEGD TNAWNHTLLL QLFLQQIARK IACTHINTFE
HDSLYWDASS NGVFTCKSAY WIATQTIEGF QDSVLTHERR SLKCIWLANI PGKVKIFAWK
ACMNLLPTVS NLMTKGLAPG SLSCVHCTAP MEDIKHALFL CNWARDVWAS MNLMDLTDQA
EEIPIEEIIT TAKDRGNETL NMMLMGMWRI WCARNSKAHG GKHVEPNEIK LSTSGILDDF
TRANVNWEEN RVTSNNPCQV RWSPPTNGVI KINADGGISS ENGVAGLGFI MRCHNGSVLV
AGNKHVAYAT SVIEVEVKAI L
//
