ID A0A2U1NPE5_ARTAN Unreviewed; 635 AA.
AC A0A2U1NPE5;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=AP180 N-terminal homology (ANTH) domain-containing protein {ECO:0000313|EMBL:PWA75379.1};
GN ORFNames=CTI12_AA243320 {ECO:0000313|EMBL:PWA75379.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA75379.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA75379.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA75379.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, clathrin-coated vesicle
CC {ECO:0000256|ARBA:ARBA00004132}. Golgi apparatus
CC {ECO:0000256|ARBA:ARBA00004555}. Membrane, clathrin-coated pit
CC {ECO:0000256|ARBA:ARBA00004600}. Vesicle
CC {ECO:0000256|ARBA:ARBA00004373}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA75379.1}.
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DR EMBL; PKPP01002421; PWA75379.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1NPE5; -.
DR STRING; 35608.A0A2U1NPE5; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0005905; C:clathrin-coated pit; IEA:UniProtKB-SubCell.
DR GO; GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005545; F:1-phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0048268; P:clathrin coat assembly; IEA:InterPro.
DR GO; GO:0072583; P:clathrin-dependent endocytosis; IEA:InterPro.
DR CDD; cd16987; ANTH_N_AP180_plant; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 1.20.58.150; ANTH domain; 1.
DR InterPro; IPR011417; ANTH_dom.
DR InterPro; IPR014712; ANTH_dom_sf.
DR InterPro; IPR048050; ANTH_N_plant.
DR InterPro; IPR045192; AP180-like.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR PANTHER; PTHR22951:SF13; ASSEMBLY PROTEIN, PUTATIVE, EXPRESSED-RELATED; 1.
DR PANTHER; PTHR22951; CLATHRIN ASSEMBLY PROTEIN; 1.
DR Pfam; PF07651; ANTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50942; ENTH; 1.
PE 4: Predicted;
KW Coated pit {ECO:0000256|ARBA:ARBA00023176};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000245207}.
FT DOMAIN 22..158
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 155..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 355..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..177
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..205
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 355..379
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 635 AA; 70051 MW; 5D5E891FFC605922 CRC64;
MAPFRKTLGA VKDQTSIGIA KVASNMAPEL EVAIVKATSH DDDPASEKHI REILQLTSYS
RGYVSACVHA VSKRLSKTRD WIVALKCLVL VHRLLNDGDS VFQQEVMYAT RKGTRLLNMA
DFRDEAHSNS WDHSTFVRTY GFYLDQRLDL IAYERKQSGG SSGDSERSRE DRWRSPQNRG
YGYDYNESRD EPGYGDMRRT RSSEDVRGGP GGSSQEKKDA TPLRDMQPER IFGKMGHLQR
LLDRVLSCRP TGLARNSRLV LVSLYPVVQE SFKLYADICE VLAVLLDKFF DMEHQDCVKA
FDAYASTAKQ IDELVGFYNW CKDMGVARSS DYPEVQRITG KLLETLEEFV RDRAKAMKSP
EKKPEVVEEV KEEEPEPPPP PKPQGDLMDL REEAFTGDDQ GNRFALALFA GPAANNGNGN
WEAFGSNGSE VTSAWQNPAA EAGKADWELA LVETTSQLEK QKATMGGGLD PLLLNGMYDQ
GMVRQHVSTS QVTGGSASSV ALPNKSATPV LALPAPDGSV QAVGGDPFAA SLSVPPPSYV
QMADIEKKQQ LLVQEQMVWQ QYAREGMQGQ VSLAKINGGG YVAPGQPPMM PYGVPPTNGA
GNNLTCRFYL VNFNSMKHLK QIVVLAQNTV DVDAS
//
