ID A0A2U1NZ98_ARTAN Unreviewed; 361 AA.
AC A0A2U1NZ98;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase domain-containing protein {ECO:0000259|Pfam:PF03171};
GN ORFNames=CTI12_AA209420 {ECO:0000313|EMBL:PWA78834.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA78834.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA78834.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA78834.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase
CC family. {ECO:0000256|ARBA:ARBA00008056}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA78834.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; PKPP01001936; PWA78834.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1NZ98; -.
DR STRING; 35608.A0A2U1NZ98; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR InterPro; IPR027443; IPNS-like_sf.
DR PANTHER; PTHR10209:SF754; ISOPENICILLIN N SYNTHASE-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR10209; OXIDOREDUCTASE, 2OG-FE II OXYGENASE FAMILY PROTEIN; 1.
DR Pfam; PF03171; 2OG-FeII_Oxy; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Reference proteome {ECO:0000313|Proteomes:UP000245207}.
FT DOMAIN 222..312
FT /note="Isopenicillin N synthase-like Fe(2+) 2OG
FT dioxygenase"
FT /evidence="ECO:0000259|Pfam:PF03171"
SQ SEQUENCE 361 AA; 40450 MW; FDE9DF97B01D940F CRC64;
MDIPVIDLTP YVDATSGEFC LDGVLSPELE KVCLEVSRIL RETGALLVKD PRCSAEDDDR
FISMMEKYFE MPDEFKLLQA RPDMHYQNGA TPGGVEVPRS LAVKDMLEKA KALPKEHQPL
IPTGADLKWR YMWRIGPRPS TTRFKDLNSE HIIPEGFPEW EEIMESWGYK LMSAVEAIAE
MVAIGFGLPK DAFTSLLKNG PHLLSPTGSD LASHGKEGTV FAGYHYDLNF LTIHYRSKFP
GLYIWLRNGK KVEVKVPEGC LLIQSGKQLE WVTAGDCMAG LHEVIVTKKT VDAIKAASEA
NRSLWRVSST LFSAVASDDI MKPLGHYAQS PLADNYPPVY AGEYFQKELA VIKLNENKKE
H
//
