ID A0A2U1P2V1_ARTAN Unreviewed; 744 AA.
AC A0A2U1P2V1;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=SPX domain, EXS {ECO:0000313|EMBL:PWA80093.1};
GN ORFNames=CTI12_AA195680 {ECO:0000313|EMBL:PWA80093.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA80093.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA80093.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA80093.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- FUNCTION: May transport inorganic phosphate (Pi).
CC {ECO:0000256|ARBA:ARBA00043939}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SYG1 (TC 2.A.94) family.
CC {ECO:0000256|ARBA:ARBA00009665}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA80093.1}.
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DR EMBL; PKPP01001766; PWA80093.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1P2V1; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR CDD; cd14476; SPX_PHO1_like; 1.
DR InterPro; IPR004342; EXS_C.
DR InterPro; IPR034092; PHO1_SPX.
DR InterPro; IPR004331; SPX_dom.
DR PANTHER; PTHR10783:SF112; EXS-RELATED; 1.
DR PANTHER; PTHR10783; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED; 1.
DR Pfam; PF03124; EXS; 1.
DR Pfam; PF03105; SPX; 1.
DR PROSITE; PS51380; EXS; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphate transport {ECO:0000256|ARBA:ARBA00022592};
KW Reference proteome {ECO:0000313|Proteomes:UP000245207};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 341..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 381..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 491..509
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 554..572
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 612..632
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 661..681
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..290
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT DOMAIN 550..744
FT /note="EXS"
FT /evidence="ECO:0000259|PROSITE:PS51380"
SQ SEQUENCE 744 AA; 86313 MW; A67313D3BDAEFCE3 CRC64;
MKFGKEFASQ MVPEWQEAYM NYNQLKNLVK EILIFRQWQA RSLNVVKPPS KATSLKRKGS
IFRAFSGLTS RFGNASVRRD KEEEEVILTS AMQHADEEQG ECLKYQTIFL RSSDDGGEFE
LMFFKRLDYE FNKVVNFYRE KVEEVVKRAE ELNIQMDAFI ALRIKVNKPA AVTPIMERNT
GEQHQENRVD DVKEHKMASL DILNRIKLNA TIKTPVSTMR SVFNSLSSDL QFNKNELKEA
QGKLKQAFIE FHEKLRYLKN YSFLNQLAFS KIMKKYDKIA KRNAADAYLQ MIEESYLGQS
DEVAKLIERV EAAFIKHFCN GNRSQGMNTL RPKARREKHR VTFFVGGFFG CALALVVVII
TDMHTKDLLK NEEKSQYMNT IFPLYSLFGF IVLHMMMYAG NVYYWARYRV NYSFIFECKP
GTELGFKQVL LISSGLSVVT LAAILANLEM DMDPNTRSYQ AVTELLPLGL VIVVGLIAIC
PFNVFYRSTR YFLLVCIWHC ICSPLYTVTL PDFFLADQFT SQVQLLRNLE FYVCYYGWGD
FKKRNAQTCT DSDIYKTISI IIAVIPYWIR FLQCVRRYFE GRDSTQALNG LKYFSTIAAV
VARSMYSQKH GMTLKIIAAS TSGIATIFST YWDLVMDWGL LNKNSENPWL RDKLILPNRS
IYFIAMVLNV ILRLAWMQTV LDFQEAPSLH RNALIAIVAS LEIIRRGIWN FFRLENEHLN
NVGKFRVVKS VPLPFSYEDE DKNL
//
