ID A0A2U1P554_ARTAN Unreviewed; 499 AA.
AC A0A2U1P554;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Mitochondrial-processing peptidase subunit alpha {ECO:0000313|EMBL:PWA80904.1};
GN ORFNames=CTI12_AA193760 {ECO:0000313|EMBL:PWA80904.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA80904.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA80904.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA80904.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|RuleBase:RU004447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA80904.1}.
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DR EMBL; PKPP01001658; PWA80904.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1P554; -.
DR STRING; 35608.A0A2U1P554; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR001431; Pept_M16_Zn_BS.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR11851:SF214; METALLOENZYME, LUXS_M16 PEPTIDASE-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR PROSITE; PS00143; INSULINASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000245207}.
FT DOMAIN 82..226
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 239..418
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 499 AA; 53443 MW; A402AB0993DC8B92 CRC64;
MYRVAASRLR TLKGRSLTRF ASSSAVAANS SSGGIFSFFT GGSSGSLPPL DFPLKGIEIP
PSLPDHVETG KTKVTTLPNG VRIASETSAN PAASIGLYVN SGSIYETPAS FGATHLLERM
AFKSTANRSH LRLVREVEAI GGNVTASASR EQMGYTFDAL KTYVPQMVEL LVDSARNQVF
LDWEVKEQIE KVKAEISEYA NNPEALLLEA IHSAGYSGAL ANPLLASEGS LNRLDSTILE
QFVAENYTAP RIVLAASGVE HEELLKYAEP LLSDLPGGAQ AAEPQSVYVG GDHRVMADTG
RTSFALAFEL PGGWLKEKDA MTLTVLQMLM GGGGSFSAGG PGKGMYSRLY LNVLNEYPDV
YSFSAFNSIY NHTAVFGIQA TTSSEFASKA IDVAAKELLA VATNGAVPQK QLDRAKQSTK
SAILMNLESR MVASEDIGRQ ILTYGERKPV EFFLKAVDEV TAKDIASLAQ KLLSSPLTMA
SHGDVIHVPT YDSVSSKFR
//
