ID   A0A2U1PHH9_ARTAN        Unreviewed;       166 AA.
AC   A0A2U1PHH9;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 11.
DE   SubName: Full=Pyruvate kinase, cytosolic isozyme {ECO:0000313|EMBL:PWA85200.1};
GN   ORFNames=CTI12_AA148970 {ECO:0000313|EMBL:PWA85200.1};
OS   Artemisia annua (Sweet wormwood).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC   Artemisiinae; Artemisia.
OX   NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA85200.1, ECO:0000313|Proteomes:UP000245207};
RN   [1] {ECO:0000313|EMBL:PWA85200.1, ECO:0000313|Proteomes:UP000245207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC   TISSUE=Leaf {ECO:0000313|EMBL:PWA85200.1};
RX   PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA   Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA   Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA   Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT   "The genome of Artemisia annua provides insight into the evolution of
RT   Asteraceae family and artemisinin biosynthesis.";
RL   Mol. Plant 11:776-788(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWA85200.1}.
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DR   EMBL; PKPP01001148; PWA85200.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U1PHH9; -.
DR   STRING; 35608.A0A2U1PHH9; -.
DR   Proteomes; UP000245207; Unassembled WGS sequence.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0030955; F:potassium ion binding; IEA:InterPro.
DR   GO; GO:0004743; F:pyruvate kinase activity; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.1380.20; Pyruvate kinase, C-terminal domain; 1.
DR   InterPro; IPR001697; Pyr_Knase.
DR   InterPro; IPR015795; Pyrv_Knase_C.
DR   InterPro; IPR036918; Pyrv_Knase_C_sf.
DR   PANTHER; PTHR11817; PYRUVATE KINASE; 1.
DR   PANTHER; PTHR11817:SF5; PYRUVATE KINASE-RELATED; 1.
DR   Pfam; PF02887; PK_C; 1.
DR   SUPFAM; SSF52935; PK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:PWA85200.1};
KW   Pyruvate {ECO:0000313|EMBL:PWA85200.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245207};
KW   Transferase {ECO:0000313|EMBL:PWA85200.1}.
FT   DOMAIN          61..163
FT                   /note="Pyruvate kinase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02887"
SQ   SEQUENCE   166 AA;  18246 MW;  2F072C17542D217C CRC64;
     MFWLAQTESC LVEKPQLGPI QNLLFVPWPR FAWKLKTPDY NDVFKMITAN APVPVSPLEI
     LASSAIRTAI SSKSSLILVL TRGGSTLKLV AKYRFGMPIL SGVVSEIKID SFDWSCSDES
     PARPSKEAIE FALQQCKEKG LCKTGDVIVA LHHVGTTSII KIVTVK
//