ID   A0A2U1PYY0_ARTAN        Unreviewed;       535 AA.
AC   A0A2U1PYY0;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   SubName: Full=IQ-domain 18 {ECO:0000313|EMBL:PWA90981.1};
GN   ORFNames=CTI12_AA095080 {ECO:0000313|EMBL:PWA90981.1};
OS   Artemisia annua (Sweet wormwood).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC   Artemisiinae; Artemisia.
OX   NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA90981.1, ECO:0000313|Proteomes:UP000245207};
RN   [1] {ECO:0000313|EMBL:PWA90981.1, ECO:0000313|Proteomes:UP000245207}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC   TISSUE=Leaf {ECO:0000313|EMBL:PWA90981.1};
RX   PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA   Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA   Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA   Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT   "The genome of Artemisia annua provides insight into the evolution of
RT   Asteraceae family and artemisinin biosynthesis.";
RL   Mol. Plant 11:776-788(2018).
CC   -!- SUBUNIT: Binds to multiple calmodulin (CaM) in the presence of Ca(2+)
CC       and CaM-like proteins. {ECO:0000256|ARBA:ARBA00024378}.
CC   -!- SIMILARITY: Belongs to the IQD family. {ECO:0000256|ARBA:ARBA00024341}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWA90981.1}.
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DR   EMBL; PKPP01000584; PWA90981.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U1PYY0; -.
DR   STRING; 35608.A0A2U1PYY0; -.
DR   Proteomes; UP000245207; Unassembled WGS sequence.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.190; -; 1.
DR   InterPro; IPR025064; DUF4005.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   PANTHER; PTHR32295; IQ-DOMAIN 5-RELATED; 1.
DR   PANTHER; PTHR32295:SF6; PROTEIN IQ-DOMAIN 17; 1.
DR   Pfam; PF13178; DUF4005; 1.
DR   Pfam; PF00612; IQ; 2.
DR   SMART; SM00015; IQ; 2.
DR   PROSITE; PS50096; IQ; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000245207}.
FT   DOMAIN          388..485
FT                   /note="DUF4005"
FT                   /evidence="ECO:0000259|Pfam:PF13178"
FT   REGION          1..90
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          195..243
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          255..410
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          440..488
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        19..60
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..90
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        195..219
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        220..243
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        260..278
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        327..384
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   535 AA;  60297 MW;  430E386867DA156E CRC64;
     MGKKGGSSWL TAVKRAFRSP SKDSSEKKTN KKTNDHSQEH DHLDDDDDKK KEKKRWLFRK
     PTTIQENVSS PQTAHPSSKQ MTHVGSSAEL AGVSEQRSAI AAAATTAAAA EVAIEVARRS
     KPPVKVNNSR HHYAATIIQT AFRGYLARRA LRALKGLVKL QALVRGHNVR KQAKMTLQCM
     QALVRVQARV LDQRMKQSDQ CSSRKSTFSD TNSAWGSRYH QDISDRRSMS RDGSSIADDW
     DERPHTIEEV KAMLQSRAAK REKTLSQAFS QETRRNNRNP SMGSDKELGV GDRHQWLDSW
     MGSKPWESRP MARASTDQRD RFKTVEVDTS QPYSTIPPNH MRRSSYQYNH QHHNHYQNQR
     NSSSSPLHRA PVTPSPSKTR PIQVRSASPH YVREDRSYHS TQSQTPSLRS NYSFNTVLQH
     PRGSTSGSGG SIPNYMAATE SAKARIRSQS APRQRPATPD RDRPGTAKKR LSFPVPDPYA
     ANSQNLRSPS FTSVNESYAY MGVEQQSNYS SYYTESIAGG EVSPCSTTDL RRWLR
//