ID A0A2U1QFR4_ARTAN Unreviewed; 951 AA.
AC A0A2U1QFR4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=PWWP domain-containing protein {ECO:0000313|EMBL:PWA96813.1};
GN ORFNames=CTI12_AA038060 {ECO:0000313|EMBL:PWA96813.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA96813.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA96813.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA96813.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA96813.1}.
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DR EMBL; PKPP01000158; PWA96813.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1QFR4; -.
DR STRING; 35608.A0A2U1QFR4; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0048188; C:Set1C/COMPASS complex; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR GO; GO:0051171; P:regulation of nitrogen compound metabolic process; IEA:UniProt.
DR CDD; cd15495; PHD_ATX3_4_5_like; 1.
DR CDD; cd15517; PHD_TCF19_like; 1.
DR CDD; cd20143; PWWP_AtATX3-like; 1.
DR CDD; cd10518; SET_SETD1-like; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR InterPro; IPR042011; ATX3/4/5_PHD.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR025780; Hist-Lys_N-MeTrfase_ATX.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF92; HISTONE-LYSINE N-METHYLTRANSFERASE ATX3; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF00855; PWWP; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 3.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR SUPFAM; SSF82199; SET domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS51566; SAM_MT43_TRX_MLL; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000245207};
KW Transferase {ECO:0000256|ARBA:ARBA00022603};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 156..224
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT DOMAIN 340..394
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 520..571
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 574..689
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 810..927
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
SQ SEQUENCE 951 AA; 108578 MW; 2297CE19FA8301F7 CRC64;
MIKQTVRSKM PSIKRCSLKE YDSEETESDD SFVADIEFAL PAKTEIDDSG SVVSSYSSNV
GDNAWFSELN SGGSVPKCTS LKERENGVID DKEVVQKKLC LYRNENDSVR KCTSLKKREN
NGFSNDKEVV QKKQCLYMNE KGDVVKGYYV CQDFVKGDIV WAKCGRWFPA WPAIVIDPLL
EAPKAVLMAC VPNTLCVMFY GFSKKGQRDY AWVKDGMVFP FKEYLASFQE QTQLYGSKPE
DFRMAIEEAR LAENALLNPV DVVKEEYCPA SELVEIPVAA ASDQDLEFFR RKQSAYNYKD
KQTCDSCGLS FHSDAMKKTK GITSQQNAFC EHCLKLRKSR QYCGICKKIW HHSDGGDWIC
CDGCDVWVHA ECADVSISED LEEFDYYCPE CTGECAVEEP IVEISEPKYR YQSVLPDKIS
VVCAGVEGIY YPKLHLVECK CGSCGIRKLH LSEWERHTGS TWKKWKDCVR VKRSLIKLEE
LLLGRNIDSF KAALALPLDE RQLFSFLQEK YEPVEAKWTS ERCAICGWDE DYDHNTIVIC
NRCHIAVHQE CYGVRDIRDF TSWVCRACET PEVKRECCLC PVKGGALKPT DIDTLWVHVI
CAWFRPEVSF VSDEKMEPAT GILRIPPDSF LKECVICKQV HGSCIKCCKC PTYFHATCAS
RAGYCIELHS SEKGGIYNTK WTPYCALHRT PADTGIVIRT SSEVFCAKRL LEKQSFRGSR
LVMCTKLEDS YSSLAENDEP ESIPAARCRV YRRSNKKNGV KEALFHRLMG PIQHSIDSID
RLNSHREVQD LSSFSTFKEK LECLKRTENL RVCFGKSGIH GWGLFARRKI QEEEMVLEYR
GERVRGSVAD LREIRYRSEG KDCYLFKVSH DIVIDATHKG NIARLINHSC MPNCYARILT
MGPHESRIVL IAKTNVSAGE ELTYDYKFEQ DENDEVKIPC LCRAPNCRTF L
//
