ID A0A2U1QJ10_ARTAN Unreviewed; 1620 AA.
AC A0A2U1QJ10;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=IQ motif, EF-hand binding site {ECO:0000313|EMBL:PWA97996.1};
GN ORFNames=CTI12_AA024570 {ECO:0000313|EMBL:PWA97996.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA97996.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA97996.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA97996.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. Plant myosin class XI subfamily.
CC {ECO:0000256|ARBA:ARBA00008049}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA97996.1}.
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DR EMBL; PKPP01000090; PWA97996.1; -; Genomic_DNA.
DR STRING; 35608.A0A2U1QJ10; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0007015; P:actin filament organization; IEA:InterPro.
DR GO; GO:0030048; P:actin filament-based movement; IEA:UniProt.
DR CDD; cd15475; MyosinXI_CBD; 1.
DR CDD; cd01384; MYSc_Myo11; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 2.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR037975; MyosinXI_CBD.
DR InterPro; IPR036018; MYSc_Myo11.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF792; MYOSIN-9; 1.
DR Pfam; PF01843; DIL; 1.
DR Pfam; PF00612; IQ; 2.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM01132; DIL; 1.
DR SMART; SM00015; IQ; 6.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51126; DILUTE; 1.
DR PROSITE; PS50096; IQ; 3.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000245207}.
FT DOMAIN 98..147
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 152..826
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1250..1562
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT REGION 707..729
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1087..1110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1153..1197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1156..1182
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 246..253
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1620 AA; 183935 MW; 3445E23BAB1EAAF2 CRC64;
MRKSKAWEIV VEGMKNLASK CQISSIIRRY IVSWLQRLKI AQGLFSAKLV VVSLEAVLKA
SQVIIDPFEK VPSMQLHHLS CYSQHFCKAK LAAPVNIILG TQVWVEDPNV CWIEGVVTKI
TGQEVEVETT DGKKVVTNLS KTYPKDVDAP AGGVDDMTKL SYLHEPGVLQ NLSTRFQLNE
IYTYTGNILI AINPFQRLTH LYETHMMEQY KGAPLGELSP HVFAIADVAF RAMIREGKSN
SILVSGESGA GKTETTKMLM RYLAYLGGRK GTEGRTVEQQ VLESNPVLEA FGNAKTVRNN
NSSRFGKFVE IQFDKHGRIS GAAIRTYLLE RSRVCQISDP ERNYHCFYLL CAAPPEEIEK
YKLGDPKSFH YLNQSNCYQL VGINEAQDYL ATRRAMDVVG ISDKEQEAIF RLVAAILHLG
NVEFIKGKEV DSSLLKDEKS KFHLKMTAEL LTCDRAALED ALLKRVMVTP EEVIKRSLNP
EAATISRDGL AKTLYSRLFD WLVNKINMSI GQDPNSKSLI GVLDIYGFES FKLNSFEQFC
INFTNEKLQQ HFNQHVFKME QEEYTKEQID WSYIEFVDNK DVLELIEKKP GGIIALLDEA
CMFPKSTHET FSQKLYQTFK SHARFVKPKL SRSDFIISHY AGEVQYQSEL FLDKNKDYVV
PEHQDLLMAS KCSFVAGLFP PIPEETNKSS SKSAKFSSIG SRFKLQLQSL METLNSTEPH
YIRCVKPNNL LKPSIFENAN IMQQLRCGGV LEAIRISMAG YPTRKSFFDF LNRFSLLAPE
VLGGNLDAKD ACKKIIDKMG LQGSQIGKTK VFLRAGQMAE LDARRAQKLN TAAKKIQRKI
RTHITRNRFL ALRKASISMQ SLCRGKLGTK LFEHMKRQAA SLKIQKNYRR HSFWMWYKKL
KLSVIVLQTG MRAMAAHSAF RHKKTTKAAL LVQANWHRHR DFKYYKNLMR SALVTQKRWR
GRAARKELRK LKMAAKETGA LQEAKDKLQK QVEDLTWRLQ LEKRLKTDLE EAKGHEIQKL
QNSLQAMQAK VDETTELLTK ERESAQKAIQ EASAIVEETA PIHVEDTEKI DKLSAEVEQL
KNLLESEKKR ADESEKKCTE ALESSESKQL KLDETVNRAN QLQESMNRLE EKLSNIESEN
KVLRQQALDM AESAKLQATR SKSTRLQRSE SQKIQSVDLH SPSMQMRDAD VEERPQKSLN
EKQQEYQDLL IRCIAQNLGF AKGRPVAACI IYKCLRQWRS FEAEKTSIFD RIIQTIGQAI
ETQDNNETLA YWLSNASTLL LLLQRTLKAS GSAGAQQHRR PTSASLFGRM TQSFRGTPQD
VNISLIDGGT AGASDTLQQV EAKYPALLFK QQLTAYVEKI YGMIRDNLKK DISPLLGLCI
QAPRISRANL LKGTAVALAS AASQDILIAH WQGIVNNIGC SLNMLKSNNV PPFLVRKIFT
QIFSFINVQL FNSLLLRREC CSFSNGEYVK AGLSELEHWC YKATEEYAGS AWDELKHIRQ
AIGFLVIHQK PKKTLDEISH DLCPVLSIQQ LYRISTMYWD DKYGTYSLSH DVISNMRVLM
TEDSNNAVSS SFLLDDDSSI PFSVDDLSKS KDQINIADIE PPPLIRDNSG FSFLLLRAET
//
