ID A0A2U1QP31_ARTAN Unreviewed; 560 AA.
AC A0A2U1QP31;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=1-phosphatidylinositol 4-kinase {ECO:0000256|ARBA:ARBA00012169};
DE EC=2.7.1.67 {ECO:0000256|ARBA:ARBA00012169};
GN ORFNames=CTI12_AA003840 {ECO:0000313|EMBL:PWA99732.1};
OS Artemisia annua (Sweet wormwood).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae;
OC Artemisiinae; Artemisia.
OX NCBI_TaxID=35608 {ECO:0000313|EMBL:PWA99732.1, ECO:0000313|Proteomes:UP000245207};
RN [1] {ECO:0000313|EMBL:PWA99732.1, ECO:0000313|Proteomes:UP000245207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Huhao1 {ECO:0000313|Proteomes:UP000245207};
RC TISSUE=Leaf {ECO:0000313|EMBL:PWA99732.1};
RX PubMed=29703587; DOI=10.1016/j.molp.2018.03.015;
RA Shen Q., Zhang L., Liao Z., Wang S., Yan T., Shi P., Liu M., Fu X., Pan Q.,
RA Wang Y., Lv Z., Lu X., Zhang F., Jiang W., Ma Y., Chen M., Hao X., Li L.,
RA Tang Y., Lv G., Zhou Y., Sun X., Brodelius P.E., Rose J.K.C., Tang K.;
RT "The genome of Artemisia annua provides insight into the evolution of
RT Asteraceae family and artemisinin biosynthesis.";
RL Mol. Plant 11:776-788(2018).
CC -!- SIMILARITY: Belongs to the PI3/PI4-kinase family. Type II PI4K
CC subfamily. {ECO:0000256|ARBA:ARBA00008941}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWA99732.1}.
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DR EMBL; PKPP01000008; PWA99732.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1QP31; -.
DR STRING; 35608.A0A2U1QP31; -.
DR Proteomes; UP000245207; Unassembled WGS sequence.
DR GO; GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IEA:UniProtKB-EC.
DR InterPro; IPR044571; P4KG1-8.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR45800:SF12; 1-PHOSPHATIDYLINOSITOL 4-KINASE; 1.
DR PANTHER; PTHR45800; PHOSPHATIDYLINOSITOL 4-KINASE GAMMA; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000245207}.
FT DOMAIN 128..418
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
SQ SEQUENCE 560 AA; 62148 MW; E86205D00B772830 CRC64;
MAAAPWKRRI FVQTETGCAL GIELDGSDDA NTVKKRLQTA LNVCIDEWLL VYGDKVLNSD
LSTVRNGSPV LLTRNVLRTS SSTPCLSPVS NETHNGDFSE PVEILVPSMQ FSSTKKLVHD
IIKAIECDIG PVPISSGLGG AYYFKNCDGD NVAIVKPTDE EPFAPNNPKG FVGRVLGQPG
LKPSVRVGET GYREVAAFLL DHDQSAKVPP TTLVKITHSI FNVNDKVNEQ VCKIASLQQY
VHHDFDASDY GSSSFPVSAV HRIGILDIRI LNTDRHGGNI LVKKPENSGK FDQVELFPID
HGLCLPESLE DPYFEWIHWP QASVPFSEDE LDYISNLDPV NDSELLRMEL PMIREACLRV
LVLCTTFLKE AASFGLCLAE IGGMMSREFH YNEEGPSELE VICIQARKLL EESEAWSPAS
KVTNKEMFQF DIECDDYSST YGNMLSDSFG SFETEESDKV TDQELLNLST SLKACSIEEQ
DWRREVTAVN GGYSASSSSG IRSMNEQLSS SVSFVTLSDM SQEEWVAFLC HFEGLLHSAF
VNCKSRNLRQ KQRLGTSCQF
//
