ID A0A2U1S5K5_9EURY Unreviewed; 174 AA.
AC A0A2U1S5K5;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=pyruvate synthase {ECO:0000256|ARBA:ARBA00012822};
DE EC=1.2.7.1 {ECO:0000256|ARBA:ARBA00012822};
GN Name=padE_2 {ECO:0000313|EMBL:PWB84952.1};
GN ORFNames=MBBWO_12630 {ECO:0000313|EMBL:PWB84952.1};
OS Methanobrevibacter woesei.
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX NCBI_TaxID=190976 {ECO:0000313|EMBL:PWB84952.1, ECO:0000313|Proteomes:UP000245577};
RN [1] {ECO:0000313|EMBL:PWB84952.1, ECO:0000313|Proteomes:UP000245577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11979 {ECO:0000313|EMBL:PWB84952.1,
RC ECO:0000313|Proteomes:UP000245577};
RA Poehlein A., Seedorf H., Daniel R.;
RT "Genome sequence of Methanobrevibacter wosei.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA
CC + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]; Xref=Rhea:RHEA:12765,
CC Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001, ChEBI:CHEBI:15361,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:33737,
CC ChEBI:CHEBI:33738, ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=1.2.7.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001135};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWB84952.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MZGU01000006; PWB84952.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1S5K5; -.
DR OrthoDB; 372091at2157; -.
DR Proteomes; UP000245577; Unassembled WGS sequence.
DR GO; GO:0047110; F:phenylglyoxylate dehydrogenase (acylating) activity; IEA:UniProtKB-EC.
DR GO; GO:0019164; F:pyruvate synthase activity; IEA:RHEA.
DR Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR InterPro; IPR011894; PorC_KorC.
DR InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR NCBIfam; TIGR02175; PorC_KorC; 1.
DR PANTHER; PTHR43366; PYRUVATE SYNTHASE SUBUNIT PORC; 1.
DR PANTHER; PTHR43366:SF1; PYRUVATE SYNTHASE SUBUNIT PORC; 1.
DR Pfam; PF01558; POR; 1.
DR SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:PWB84952.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000245577}.
FT DOMAIN 10..172
FT /note="Pyruvate/ketoisovalerate oxidoreductase catalytic"
FT /evidence="ECO:0000259|Pfam:PF01558"
SQ SEQUENCE 174 AA; 19118 MW; 9140103BD7B62A92 CRC64;
MIEIRFHGRG GQGSVTAAEI LAKAAFKDGK YVQAFPFFGV ERRGAPVMAF TRIDDKPIDI
RYQIYTPDYV LVLDDGLMNV IDVFSGAKEN TEVIINIAEE FKGKVDVPVH SIDATGIALD
MLGRNIVNTI ILGYFAKKTQ VVSIDSLIEV IKETFPGKVG ELNAEATKKA YEMG
//
