ID A0A2U1S807_9EURY Unreviewed; 503 AA.
AC A0A2U1S807;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=MBBWO_11070 {ECO:0000313|EMBL:PWB86253.1};
OS Methanobrevibacter woesei.
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX NCBI_TaxID=190976 {ECO:0000313|EMBL:PWB86253.1, ECO:0000313|Proteomes:UP000245577};
RN [1] {ECO:0000313|EMBL:PWB86253.1, ECO:0000313|Proteomes:UP000245577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11979 {ECO:0000313|EMBL:PWB86253.1,
RC ECO:0000313|Proteomes:UP000245577};
RA Poehlein A., Seedorf H., Daniel R.;
RT "Genome sequence of Methanobrevibacter wosei.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the HerA family.
CC {ECO:0000256|ARBA:ARBA00007816}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWB86253.1}.
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DR EMBL; MZGU01000004; PWB86253.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U1S807; -.
DR OrthoDB; 107033at2157; -.
DR Proteomes; UP000245577; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR018538; HerA_barrel_dom.
DR InterPro; IPR033186; HerA_C.
DR InterPro; IPR002789; HerA_central.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR42957; HELICASE MJ1565-RELATED; 1.
DR PANTHER; PTHR42957:SF1; HELICASE MJ1565-RELATED; 1.
DR Pfam; PF01935; DUF87; 1.
DR Pfam; PF09378; HAS-barrel; 1.
DR Pfam; PF05872; HerA_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000245577}.
FT DOMAIN 3..86
FT /note="Helicase HerA barrel"
FT /evidence="ECO:0000259|Pfam:PF09378"
FT DOMAIN 121..329
FT /note="Helicase HerA central"
FT /evidence="ECO:0000259|Pfam:PF01935"
FT DOMAIN 353..458
FT /note="Helicase HerA-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05872"
SQ SEQUENCE 503 AA; 56587 MW; 3A2954ADA8A49C8F CRC64;
MIIGRCMGET SLTELTFISN KMPNVGEYVS MNYDGKLILG MIEDLVRGNV ALNSEIYNTE
DIERIVEYGL DEFYVKGKIR VLGDINNHLK LPRTPAPPGT PIELASEAIL KKVFTVDNPL
KLGTLINQDD VEVSVNANSF LNRHLAILAM TGAGKSNTVC VLIDGLLDYN VPVFIFDMHG
EYVNAEFVNG EVNVIRPTIN PRYMSFTEIK KLANIPNNAY KQERHFRKAF KEANQAVEDG
LANSNDFLEI IKNVLEIKYN DDDKPADERN NILAVLNKIE DLIEKYSNLF NVNEGNILSK
IQVGKANVLD LSQTDEYAAE VLVSHILRNS LQRRKNAFHK NSTATLDFPV FYILEEAHIL
APHKRDSNSK FWIQRVAREG RKFGLGLCLV SQSPKTVDQD ALSQMNNMII LRLVEPDDQR
HVQAASESLS SDLVKQLPSL NVGEAIILGL MTKVPTLVKI DEFKGRTHGG DIDVIAELAD
FRKKEEAELK QQEEDSFNLG YDY
//
