ID   A0A2U1SXZ8_9MICO        Unreviewed;       290 AA.
AC   A0A2U1SXZ8;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=DNA/RNA non-specific endonuclease {ECO:0008006|Google:ProtNLM};
GN   ORFNames=DF220_00430 {ECO:0000313|EMBL:PWB96479.1};
OS   Salinibacterium hongtaonis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC   Salinibacterium.
OX   NCBI_TaxID=2079791 {ECO:0000313|EMBL:PWB96479.1, ECO:0000313|Proteomes:UP000244978};
RN   [1] {ECO:0000313|Proteomes:UP000244978}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S1194 {ECO:0000313|Proteomes:UP000244978};
RA   Liu S., Wang Z., Li J.;
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWB96479.1}.
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DR   EMBL; QEEX01000001; PWB96479.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U1SXZ8; -.
DR   Proteomes; UP000244978; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd00091; NUC; 1.
DR   Gene3D; 3.40.570.10; Extracellular Endonuclease, subunit A; 1.
DR   InterPro; IPR001604; DNA/RNA_non-sp_Endonuclease.
DR   InterPro; IPR044929; DNA/RNA_non-sp_Endonuclease_sf.
DR   InterPro; IPR020821; Extracellular_endonuc_su_A.
DR   InterPro; IPR044925; His-Me_finger_sf.
DR   InterPro; IPR040255; Non-specific_endonuclease.
DR   PANTHER; PTHR13966:SF5; ENDONUCLEASE G, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR13966; ENDONUCLEASE RELATED; 1.
DR   Pfam; PF01223; Endonuclease_NS; 1.
DR   SMART; SM00892; Endonuclease_NS; 1.
DR   SMART; SM00477; NUC; 1.
DR   SUPFAM; SSF54060; His-Me finger endonucleases; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR640255-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244978}.
FT   DOMAIN          43..264
FT                   /note="DNA/RNA non-specific endonuclease"
FT                   /evidence="ECO:0000259|SMART:SM00892"
FT   DOMAIN          44..264
FT                   /note="Extracellular Endonuclease subunit A"
FT                   /evidence="ECO:0000259|SMART:SM00477"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        105
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR640255-1"
FT   BINDING         141
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR640255-2"
SQ   SEQUENCE   290 AA;  32118 MW;  D35F666D8BFCF57C CRC64;
     MTAQSAQQSA QDAPADSGYS PDFLQAPVPL PRASSDRDII ELDYTHFTVL LDRPRRLAAA
     TAVNIDGAFL VDVERGDYWH LDERIPATDQ AGPELYRGND LDRGHLVRRR DPVWGEPDVA
     ARANFDTFVY TNAAPQVAGF NQSQVLWSGL EDYVLEHARV WDLHLTVFTG PIFTAADPLY
     RGIQIPLAFW KVAAWVSEGD TLASTGYVLD QSAALREIEL TQARREAEDL RPVPPLGAFG
     TFQVPITDIE ELTRLNLGPL ARADRLPAAP PSVEGRSRWV PLRSHSDIVV
//