ID   A0A2U1T786_9CORY        Unreviewed;       622 AA.
AC   A0A2U1T786;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:PWC01864.1};
GN   ORFNames=DF222_04590 {ECO:0000313|EMBL:PWC01864.1};
OS   Corynebacterium yudongzhengii.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC   Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=2080740 {ECO:0000313|EMBL:PWC01864.1, ECO:0000313|Proteomes:UP000244989};
RN   [1] {ECO:0000313|Proteomes:UP000244989}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2189 {ECO:0000313|Proteomes:UP000244989};
RA   Liu S., Wang Z., Li J.;
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWC01864.1}.
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DR   EMBL; QEEZ01000007; PWC01864.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U1T786; -.
DR   Proteomes; UP000244989; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   Gene3D; 3.30.450.330; -; 1.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244989};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          48..233
FT                   /note="Penicillin-binding protein dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF03717"
FT   DOMAIN          280..598
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
FT   REGION          603..622
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   622 AA;  66491 MW;  971E7882AB3BB861 CRC64;
     MSRRLRIIVA VLVGLALILA GRLAWVQLAW GPSLQAQAEE QRARVYVEPA RRGMIVDHAG
     NELAYTMQAR SLTVSPNLLR DELREREELE MQADGSAEGL SAEELNNEVT TRVEDILEEM
     ATTIPEMISD TGASSDKVDK DQIHDKLTAD SSYEVLVRNV DPDVAAEVAN RFHGVAADHQ
     DIRQYPNGAI AENVLGRVSM DGEGQFGLEA SADHLLSGIN GRSTEDIATT GQVIPGTLRD
     QVPAVDGTDL QLTLDLDLQT FVQQKLEQAK ANSGAESAEA VVLDVQTAEV LAMANTDTIN
     PNKNVEEQIE DGKSFENSTI SHPYEPGSVG KIITAAGAIN DGVTTPDEMH YVPGSIDMAG
     VTVSDAWEHA GTNYTTTGIF GKSSNVGTLM LAQRLGEERF DHYLDAFGIG ETTGIELPSE
     SPGLRPPLEQ WSGGTFANLP IGQGMSWTTL QMASVFQTVA NDGERIEPRI IGEQRGPDGE
     ILEQEEPERT QVISPEAART VTDMFRATLQ SDPAGIQSGT AAASGIEGYQ LSGKTGTAQK
     VDPDTGAYSN SAYWITFAGI APADDPRFVV AVMIDEPERG VEEGGGGGQS AAPVFQDIAG
     WLLDKENIPP SPEGEPLVLQ GG
//