ID   A0A2U2B6B3_9BACT        Unreviewed;       977 AA.
AC   A0A2U2B6B3;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=FAD-binding oxidoreductase {ECO:0000313|EMBL:PWD98595.1};
GN   ORFNames=DDZ16_14110 {ECO:0000313|EMBL:PWD98595.1};
OS   Marinilabilia rubra.
OC   Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Marinilabiliaceae;
OC   Marinilabilia.
OX   NCBI_TaxID=2162893 {ECO:0000313|EMBL:PWD98595.1, ECO:0000313|Proteomes:UP000244956};
RN   [1] {ECO:0000313|EMBL:PWD98595.1, ECO:0000313|Proteomes:UP000244956}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WTE16 {ECO:0000313|EMBL:PWD98595.1,
RC   ECO:0000313|Proteomes:UP000244956};
RA   Zhang R.;
RT   "Marinilabilia rubrum sp. nov., isolated from saltern sediment.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWD98595.1}.
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DR   EMBL; QEWP01000012; PWD98595.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U2B6B3; -.
DR   OrthoDB; 9767256at2; -.
DR   Proteomes; UP000244956; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.465.10; -; 1.
DR   Gene3D; 3.30.70.2740; -; 1.
DR   Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR   Gene3D; 3.30.43.10; Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016167; FAD-bd_PCMH_sub1.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR   InterPro; IPR009051; Helical_ferredxn.
DR   InterPro; IPR006094; Oxid_FAD_bind_N.
DR   InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR   PANTHER; PTHR11748:SF119; D-2-HYDROXYGLUTARATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11748; D-LACTATE DEHYDROGENASE; 1.
DR   Pfam; PF02913; FAD-oxidase_C; 1.
DR   Pfam; PF01565; FAD_binding_4; 1.
DR   Pfam; PF13534; Fer4_17; 1.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244956}.
FT   DOMAIN          33..274
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51387"
FT   DOMAIN          615..648
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
SQ   SEQUENCE   977 AA;  108967 MW;  626F4D9D76232E76 CRC64;
     MNPVFKKLSS RIKGKIFTDE LFRTLYATDA SVYREMPQAV VFPADEADVK KLVLFAGQYN
     ISLIPRTAGT SLAGQVVGNG IVVDVSRTFT EILEVNKEKG WVSVQPGVIR DELNLFLKDH
     GLIFGPETST SNRAMIGGMV GNNSSGSNSL IYGSTRDNIL EVRGFLSDGS EVTFGALTKD
     EFLTKCESGQ QDLESSLYHQ IYDALKDVGT RGNIEGEFPK ASIKRRNTGY ALDALTASVP
     FNDNGEHFNF SKVIAGSEGT LMFITEIKLK CHPLPPQSKG LLCVHFYSME EALNANVIAL
     KHHPSASELM DDFILNCTKN NPEQSQNRFF IESDPKALLV VEFTRHSMEE VQAGIKKLTE
     DLKQAGLGYH FPLISGDDIK KVWSLRKAAL GLLYTTPGDA KPVAVIEDTS VAPDDLPSYV
     MDFREILDKL GLECVFYGHA GSGELHLRPV IDLKTEEGHR LFRRVAEETA CLVKKYRGSL
     SGEHGDGRLR GEFIHQMVGE KNYELFKVIK NTWDPKHIFN PGKIVEAPPM DSDLRYSPAS
     LTPDIETVFD FSREQGYLRA AEFCNGSGDC RKTHLSGGTM CPSYMATRDE KHTTRARANV
     LREYLRKPYV KNRFNHYEIY DVMDLCLSCK ACKSECPSSV DVAKLKAEFL QHYYEVHGVP
     LRTKMIAGFA SLNRLASVLP GVFNFMAGQK MLSEIFKKTV GFAPKRSIPK LQKTTFSKWF
     QKEQKNQVAT EEKRNGKVCL FNDEFTNYND LGIGQKAVWL LESLGYEVAM PKHIESGRAY
     ISKGLLNKAK EIAIKNVSLL KELISEDTPL IGIEPSAILT FRDEYIDLVD DDLREAARNL
     GKNALLFDEF ILSEIKSGRI TSESFTDSPQ KIMLHGHCHQ KSLASMAPTI EMLSLPANYE
     VEVIPSGCCG MAGAFGYEKE HYDISMKVGE LVLFPAIRQK EANTMVAAPG TSCRHQIKDG
     TGEKAIHPIE ILWEAKR
//