ID A0A2U2BBN9_9BACT Unreviewed; 370 AA.
AC A0A2U2BBN9;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=2-iminoacetate synthase ThiH {ECO:0000313|EMBL:PWE00479.1};
GN Name=thiH {ECO:0000313|EMBL:PWE00479.1};
GN ORFNames=DDZ16_06000 {ECO:0000313|EMBL:PWE00479.1};
OS Marinilabilia rubra.
OC Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Marinilabiliaceae;
OC Marinilabilia.
OX NCBI_TaxID=2162893 {ECO:0000313|EMBL:PWE00479.1, ECO:0000313|Proteomes:UP000244956};
RN [1] {ECO:0000313|EMBL:PWE00479.1, ECO:0000313|Proteomes:UP000244956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WTE16 {ECO:0000313|EMBL:PWE00479.1,
RC ECO:0000313|Proteomes:UP000244956};
RA Zhang R.;
RT "Marinilabilia rubrum sp. nov., isolated from saltern sediment.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWE00479.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QEWP01000003; PWE00479.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U2BBN9; -.
DR OrthoDB; 9801120at2; -.
DR Proteomes; UP000244956; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR010722; BATS_dom.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR012726; ThiH.
DR InterPro; IPR034428; ThiH/NoCL/HydG-like.
DR NCBIfam; TIGR02351; thiH; 1.
DR PANTHER; PTHR43583; 2-IMINOACETATE SYNTHASE; 1.
DR PANTHER; PTHR43583:SF1; 2-IMINOACETATE SYNTHASE; 1.
DR Pfam; PF06968; BATS; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01081; cleavage_of_the_Ca-Cb_bond_in; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00876; BATS; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000244956};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 70..297
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 370 AA; 43079 MW; 857F5280096DEC3A CRC64;
MSFYDEIKKY NWEEITTRIY KKTADDVKRA LGKDKLTIND FQALISPAAK PYLELMAQKS
MQLTQKRFGK TIQFYVPMYV SNACTNSCVY CGFNLNNQFD KTILTKQQVL AEARKLREEG
FEHLLLVSGE SSKDCGVEYF EEMMAALSDK FSLISIEIQP LKTEEYKRLT KHGLNTVYVY
QETYNESNYR KYHPAGKKSN YQYRLETPDR LGEAGVHKVG LGCLIGLEDW RVDSFFTALH
LQYLENKYWR TKYSISFPRL RPHLGTFEPN YKTSHRDLLQ IICAYRLFNE HVELSLSTRE
EPKFRDNMLK LGVTAYSAGS KTNPGGYSGN EETTEQFSVH DDRSPAEIAS VIKEQGYEVV
WKDWDSYMQK
//
