ID A0A2U2BBR4_9BACT Unreviewed; 687 AA.
AC A0A2U2BBR4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN ORFNames=DDZ16_06195 {ECO:0000313|EMBL:PWE00515.1};
OS Marinilabilia rubra.
OC Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Marinilabiliaceae;
OC Marinilabilia.
OX NCBI_TaxID=2162893 {ECO:0000313|EMBL:PWE00515.1, ECO:0000313|Proteomes:UP000244956};
RN [1] {ECO:0000313|EMBL:PWE00515.1, ECO:0000313|Proteomes:UP000244956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WTE16 {ECO:0000313|EMBL:PWE00515.1,
RC ECO:0000313|Proteomes:UP000244956};
RA Zhang R.;
RT "Marinilabilia rubrum sp. nov., isolated from saltern sediment.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWE00515.1}.
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DR EMBL; QEWP01000003; PWE00515.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U2BBR4; -.
DR OrthoDB; 9809039at2; -.
DR Proteomes; UP000244956; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000244956}.
FT DOMAIN 201..530
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 222..229
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 687 AA; 79672 MW; E73D66823CCBEA40 CRC64;
MFNGSEKEER VFLQKILERL RYTLRKIDGT ISEHSKDVQD FKEYLWNNMS DMDHAEKVSV
RQSITQTAMT GESALERKKR IRKLIDIPYF GRIDFAEEDQ KQPWPIYIGI HSFYDFETRE
NLIHDWRAPI SGMFYDYELG PAVFKVPDGE VEGEISLKRQ YRIRKSTMEF MLESSLNIHD
DVLQKELSAT SDEKMKNIVA TIQREQNAII RDEDAFVLII QGVAGSGKTS IALHRIAYLL
YRFKDTISSD NILIISPNKV FGDYIANVLP ELGEEKILET GMEDIAREQL NNKYKFQTFF
EQVSDLVHKK DEAFSERIRF KATFEFLNLL KKYLLHIENH YFEANDVKVD RFFIPAGYAE
ERFRAWSRVP LAKRFQRVAK DIVGRVEIMQ KTDIPKSEIK KTETQVKKMF RITNLQSLYK
DFYDWLQRPD MFKKRKGGLE FADVFPMVYL KIMFEGPQSA SKIKHLLVDE MQDYTPVQYA
VLSKLYPCRK TILGDANQSV NPFSSSKHED ISRVFPNAVT MKLNKSYRST FEITSFAQNI
SPNDELDPII RHGKEPQITG VKTAGNELGK ISGLIEEFQQ SSNQSLGIIC KNQEQADSIH
EQLKPHHNDV YLLNSESVAF VNGIVITTAH MAKGLEFDNV IVPHVNKKNY NNEVDKSMLY
IACTRAMHQL NLTHCGELSE LLRFPGN
//
