ID A0A2U2BCI0_9BACT Unreviewed; 777 AA.
AC A0A2U2BCI0;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=pH regulation protein AB {ECO:0000313|EMBL:PWE00772.1};
GN ORFNames=DDZ16_04040 {ECO:0000313|EMBL:PWE00772.1};
OS Marinilabilia rubra.
OC Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Marinilabiliaceae;
OC Marinilabilia.
OX NCBI_TaxID=2162893 {ECO:0000313|EMBL:PWE00772.1, ECO:0000313|Proteomes:UP000244956};
RN [1] {ECO:0000313|EMBL:PWE00772.1, ECO:0000313|Proteomes:UP000244956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WTE16 {ECO:0000313|EMBL:PWE00772.1,
RC ECO:0000313|Proteomes:UP000244956};
RA Zhang R.;
RT "Marinilabilia rubrum sp. nov., isolated from saltern sediment.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWE00772.1}.
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DR EMBL; QEWP01000002; PWE00772.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U2BCI0; -.
DR OrthoDB; 9807568at2; -.
DR Proteomes; UP000244956; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR025383; MrpA_C/MbhD.
DR InterPro; IPR046806; MrpA_C/MbhE.
DR InterPro; IPR001750; ND/Mrp_mem.
DR InterPro; IPR001516; Proton_antipo_N.
DR PANTHER; PTHR43373:SF1; ANTIPORTER SUBUNIT MNHA2-RELATED; 1.
DR PANTHER; PTHR43373; NA(+)/H(+) ANTIPORTER SUBUNIT; 1.
DR Pfam; PF13244; MbhD; 1.
DR Pfam; PF20501; MbhE; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR Pfam; PF00662; Proton_antipo_N; 1.
DR PRINTS; PR01434; NADHDHGNASE5.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000244956};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000320};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 33..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 455..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 496..522
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 571..589
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 604..624
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 631..649
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 655..677
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 689..707
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 752..770
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 70..112
FT /note="NADH-Ubiquinone oxidoreductase (complex I) chain 5
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00662"
FT DOMAIN 128..406
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
FT DOMAIN 614..677
FT /note="MrpA C-terminal/MbhD"
FT /evidence="ECO:0000259|Pfam:PF13244"
FT DOMAIN 688..767
FT /note="MrpA C-terminal/MbhE"
FT /evidence="ECO:0000259|Pfam:PF20501"
SQ SEQUENCE 777 AA; 85557 MW; 796D1D6E5E189DEE CRC64;
MEQLAIVLIG LIFLMGLMVP LLRPLFKNYT GRILALVPFA LFGALTILFF TLPDQTSRII
ETGFGFLPEM QFTFRIDGVS LIFGMMVSGI GGLVLGYSSF YMAKYAGRTK FYFFLVLFMG
AMLGLVFADN LLALFIFWEL TSITSFFLIG FDHDKEKPRQ ASLQALLLTA FGGLCLLFAV
ILIGNLAGTY SLSELYDKGF RFGAHSDYHL VFLLVSVAVA TKSAQFPFHF WLPGAMNAPT
PISAYLHSAT MVNAGIFLLL RLNPVLGGTI LWKSALILAG GITMFIGAFF ALGQKDLKRI
LAFTTISALG TMVMLIGMNT SASIKAALIF FIVHGLYKGG LFMVAGIIDK NTGTRDIDKL
GGLLKTMPIT SIAGILALLS MSGLPPMLGF IGKELIYDAK VQIPELSWLV IPLGVAANMM
MVAISVLVFY EIFLSRRNKK PIALKQPEKR LPGNFLAGPV ALALVGLGLG MAPGWLEDTM
ANAMYFIQSE VVDIDLALWH GFNQVLLLSI FTVAMGVLIF VFRRPIGKLV RIIIGWTDQY
HLPDHFNKLI KNYLSFAGKH TNRIQHGYHR YYLMTFFAAT FVLVIYQLFS ADDGWFPVKQ
VSPLQIHVIV VLLVAMMGVI FAIFTKSRIS AIISLGVLGY GISVLYMLYG AVDLAITQFL
AETVIMVIFV MVIYHLPDFA VLSSKKSRVR DALIAAGVGV MITLIVLKAR FINLETPVSE
FFAENSFLEG HGRNIVNVIL VDFRALDTLG EITVLGLAAA GVFSLLRFDL KDKNTKK
//
