ID   A0A2U2CI42_9RHOB        Unreviewed;       459 AA.
AC   A0A2U2CI42;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=Multidrug-efflux transporter {ECO:0000256|ARBA:ARBA00031636};
GN   ORFNames=C4N9_00595 {ECO:0000313|EMBL:PWE31548.1};
OS   Pararhodobacter marinus.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Pararhodobacter.
OX   NCBI_TaxID=2184063 {ECO:0000313|EMBL:PWE31548.1, ECO:0000313|Proteomes:UP000244940};
RN   [1] {ECO:0000313|EMBL:PWE31548.1, ECO:0000313|Proteomes:UP000244940}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIC4N-9 {ECO:0000313|EMBL:PWE31548.1,
RC   ECO:0000313|Proteomes:UP000244940};
RA   Lai Q.Sr., Liu X., Shao Z.;
RT   "Pararhodobacter marina sp. nov., isolated from deep-sea water of the
RT   Indian Ocean.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWE31548.1}.
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DR   EMBL; QEYD01000001; PWE31548.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U2CI42; -.
DR   OrthoDB; 9780160at2; -.
DR   Proteomes; UP000244940; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR   CDD; cd13131; MATE_NorM_like; 1.
DR   InterPro; IPR002528; MATE_fam.
DR   InterPro; IPR048279; MdtK-like.
DR   NCBIfam; TIGR00797; matE; 1.
DR   PANTHER; PTHR43298:SF2; FMN_FAD EXPORTER YEEO-RELATED; 1.
DR   PANTHER; PTHR43298; MULTIDRUG RESISTANCE PROTEIN NORM-RELATED; 1.
DR   Pfam; PF01554; MatE; 2.
DR   PIRSF; PIRSF006603; DinF; 1.
PE   4: Predicted;
KW   Antiport {ECO:0000256|ARBA:ARBA00022449};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000244940};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        25..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        63..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        108..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        143..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        173..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        212..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        252..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        285..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        327..350
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        365..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        407..429
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        435..456
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   459 AA;  48470 MW;  185BA8B408F822D3 CRC64;
     MAPPPGGASL PPTPVRRSFS ANARAVLVLG LPLIGSHVAQ FALHVTDTIM LGWYGVTDLA
     AGALGATVFF VLFTMGIGFS QAVMPMVATS AASGEDTEVR RVTRMGMWLS LIYFVIVLPV
     FLFSAPILNL LGQDPEVARL GGAYLAIVGW GLAPALLAMV LKSYLAALER TQVVLWATLL
     GVAVNIGVNW LLIFGNLGFP ELGARGAATA SVLVQLVTLG ALLAYALWLP ALRHYQLLVR
     FWRPDWAALR QVNALGLPIG LALLAETGLF AASAVMMGWL GKEMLAAHSI ALEITAMFFM
     VHLGLSNAAT VLVGRARGQR NPEALRAAAK ASVVISLAFA VATMGVYLIF AEPMVGLFLK
     PDDPARAVIV PMGASLLMVA ALFQLADGGQ VMAMGLLRGM QDTRQPMVIA AVSYWLIGLP
     AGYALGFILG WEGTGVWLGL VAGLTCAAVA LHARFWRSI
//