ID A0A2U2J5J0_9SPHN Unreviewed; 601 AA.
AC A0A2U2J5J0;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Sodium:proton exchanger {ECO:0000313|EMBL:PWG03587.1};
GN ORFNames=DF286_12415 {ECO:0000313|EMBL:PWG03587.1};
OS Sphingosinicella humi.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingosinicellaceae; Sphingosinicella.
OX NCBI_TaxID=2068657 {ECO:0000313|EMBL:PWG03587.1, ECO:0000313|Proteomes:UP000245916};
RN [1] {ECO:0000313|EMBL:PWG03587.1, ECO:0000313|Proteomes:UP000245916}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QZX222 {ECO:0000313|EMBL:PWG03587.1,
RC ECO:0000313|Proteomes:UP000245916};
RA Qiao Z., Wang G.;
RT "Genome of Sphingosinicella humi QZX222.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWG03587.1}.
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DR EMBL; QFFF01000001; PWG03587.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U2J5J0; -.
DR OrthoDB; 9781411at2; -.
DR Proteomes; UP000245916; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR006036; K_uptake_TrkA.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR46157; K(+) EFFLUX ANTIPORTER 3, CHLOROPLASTIC; 1.
DR PANTHER; PTHR46157:SF4; K(+) EFFLUX ANTIPORTER 3, CHLOROPLASTIC; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR PRINTS; PR00335; KUPTAKETRKA.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 4: Predicted;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000245916};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 310..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 418..540
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT REGION 567..601
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 601 AA; 63878 MW; 0DFC0D56BFC16DBF CRC64;
MGPATAPVEQ VAVEATALVL RDGVILLGAA MLFVTLFRRF GLGAVLGYLV AGALVGPDGL
GLVNAGEAML HIADFGIVLL LFLVGLELNP SRLWRLKQDI FGFGLLQVVV TGLALTGLVY
VATGFTLAAS LAIGLPLALS STAQVLPSLR SSGDIHGPTG ERAFSILLFQ DLSIVPLITI
IAALSRAPAD PSTPPGWLLG IYTVAAIVGL VLAGRFIINP LFRIVGRVSE RELFVVAGLF
TVLASAAVME ALHLSTALGA FVAGVMLADS PYRHELEADI EPFRSILLGL FFVAVGMMLD
IGAIASRPGF VIGMALALIA VKAAVLFALA RMFGMDNRRA VKLGLLLSQG GEFGFVLFAA
AQSAMLIATE AASLFGAIVT ISMASTPFLM KFNDWMDRRA GGREDAGLEG PEASPEAGAI
VIGYGRFGQT VAQMLMAKGI GVTLIDSRPE QIEASGAFGM KVYYGDGTRL DLLRSAGAAE
ARALLFCHDG IRLGKARLEP ILEAFPQAAV FVRAFDRRHL MDLDGLDLSG AYREVFESAI
LMGREALGQL GLPEEEVARV ERAYRDRDRE RLEEQSKSGD LHTLKERMFR PDNPLDDADP
V
//
