ID   A0A2U2JCT4_9FLAO        Unreviewed;       382 AA.
AC   A0A2U2JCT4;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Cystathionine gamma-synthase {ECO:0000313|EMBL:PWG06149.1};
GN   ORFNames=DIS07_06890 {ECO:0000313|EMBL:PWG06149.1};
OS   Polaribacter aquimarinus.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae.
OX   NCBI_TaxID=2100726 {ECO:0000313|EMBL:PWG06149.1, ECO:0000313|Proteomes:UP000245670};
RN   [1] {ECO:0000313|EMBL:PWG06149.1, ECO:0000313|Proteomes:UP000245670}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ZY113 {ECO:0000313|EMBL:PWG06149.1,
RC   ECO:0000313|Proteomes:UP000245670};
RA   Lu D.;
RT   "Polaribacter aquimarinus sp. nov., isolated from sediment in a sediment of
RT   sea.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|RuleBase:RU362118};
CC   -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC       {ECO:0000256|ARBA:ARBA00009077, ECO:0000256|RuleBase:RU362118}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWG06149.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; QFFG01000002; PWG06149.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U2JCT4; -.
DR   OrthoDB; 9803729at2; -.
DR   Proteomes; UP000245670; Unassembled WGS sequence.
DR   GO; GO:0016846; F:carbon-sulfur lyase activity; IEA:UniProt.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR   CDD; cd00614; CGS_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR11808:SF92; CYSTATHIONINE GAMMA-SYNTHASE; 1.
DR   PANTHER; PTHR11808; TRANS-SULFURATION ENZYME FAMILY MEMBER; 1.
DR   Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR   PIRSF; PIRSF001434; CGS; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR001434-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245670}.
FT   MOD_RES         197
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ   SEQUENCE   382 AA;  41925 MW;  D49F4C4F1B5C136A CRC64;
     MKFNTKTIHG GQKPEEATGS VMPPVFLTST FAQSSPGNHK GYAYGRGTNP TRTALENSFA
     AIENGTHGFA FASGMAAIDC VLRLLKPGDE VIAGDDLYGG TYRMFTQLFQ KYGLEFSYVD
     MDDVKNVSDA ITQKTKLIWI ETPTNPLMKI ADIESISSSV KEVNSNIIVA VDNTFATPYL
     QKPLDLGADI VMHSATKYLG GHSDLLMGAL MVKDEKLAKE IHFIQFAAGA IAAPMDSFLA
     LRGIKTLHIR MQRHCENGKA VAKFLKNHPK VGEVYYPGFK DHPNHEVATK QMKDFGGMVS
     FRLKDQSKEV AFQFLENTQI FTLAESLGGV ESLVNHPVTM SHGSIPEKER LKVGITDSLI
     RLSVGIEDIE DLLADLEFAL NT
//