ID A0A2U2MVT8_9GAMM Unreviewed; 627 AA.
AC A0A2U2MVT8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Formate dehydrogenase subunit alpha {ECO:0000313|EMBL:PWG60906.1};
DE Flags: Fragment;
GN ORFNames=DEM34_19205 {ECO:0000313|EMBL:PWG60906.1};
OS Spiribacter halobius.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Spiribacter.
OX NCBI_TaxID=2182432 {ECO:0000313|EMBL:PWG60906.1, ECO:0000313|Proteomes:UP000245474};
RN [1] {ECO:0000313|EMBL:PWG60906.1, ECO:0000313|Proteomes:UP000245474}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E85 {ECO:0000313|EMBL:PWG60906.1,
RC ECO:0000313|Proteomes:UP000245474};
RA Zheng W.-S., Lu D.-C., Du Z.-J.;
RT "Spiribacter halobius sp. nov., a moderately halophilic bacterium isolated
RT from marine solar saltern.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWG60906.1}.
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DR EMBL; QFFI01000075; PWG60906.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U2MVT8; -.
DR OrthoDB; 9810782at2; -.
DR Proteomes; UP000245474; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd02753; MopB_Formate-Dh-H; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR041924; Formate_Dh-H_N.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR006655; Mopterin_OxRdtase_prok_CS.
DR PANTHER; PTHR43105:SF15; FORMATE DEHYDROGENASE H; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00490; MOLYBDOPTERIN_PROK_2; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000245474}.
FT DOMAIN 16..72
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
FT NON_TER 627
FT /evidence="ECO:0000313|EMBL:PWG60906.1"
SQ SEQUENCE 627 AA; 67791 MW; 1F2BB32CC33C5A7C CRC64;
MKRFEAGAAA PALDEIREVP TLCPYCGVGC ALAYGVDRAG TIHYARGRDG ASNAGRLCVK
GRYGFDYTSH PQRLTRPLVR RDAAYPRGPL SAFSRPGASG PRKPGGIVDY AEVLPHFREA
SWAEALDRVA AGLAGVRDRH GADAVAGFGS AKGSNEEAYL FQKFIRAVIG TNNVDHCTRL
CHASSVYALM EGIGSGAVTN VVRDVENAEV AVIAGCNPTA NHPVAATFIK QAAAAGTKLL
AVNVRRPGLA DYAQQYCQIR PGTDVAFYNA VMHVLIDEGL HDRAFVAERT EGFEALRAVV
ARYSPEAVAG ITGVPADEIA GFARTLGRAR SAMFFWGMGI SQHVFGTDNA RCLIALALLT
GNIGRPGTGL HPLRGQNNVQ GASDAGLIPM YYPGYQKVAD ATVRARFEGL WGVPLSPEPG
LTTAEITHAA LEGRIRALYC MGENPFLSDP DVNRVRESLS SLEFLAVQDI FLTETAEFAD
VVLPASSFME KRGSYTNTDR RVQLGRPVRE PPGEAREDWR IIAALARRLG HDWDYADEAA
IFDELVAAAP LYANLSHERL GDNGRWYPCP SPESDGERLL FTERFPIGRG RFVPAELGEA
PDLPDAEYPL VLNTGRQLEH WHTGVMT
//
