ID   A0A2U2N2M1_9GAMM        Unreviewed;       294 AA.
AC   A0A2U2N2M1;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Prephenate dehydrogenase/arogenate dehydrogenase family protein {ECO:0000313|EMBL:PWG63471.1};
GN   ORFNames=DEM34_07860 {ECO:0000313|EMBL:PWG63471.1};
OS   Spiribacter halobius.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC   Ectothiorhodospiraceae; Spiribacter.
OX   NCBI_TaxID=2182432 {ECO:0000313|EMBL:PWG63471.1, ECO:0000313|Proteomes:UP000245474};
RN   [1] {ECO:0000313|EMBL:PWG63471.1, ECO:0000313|Proteomes:UP000245474}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E85 {ECO:0000313|EMBL:PWG63471.1,
RC   ECO:0000313|Proteomes:UP000245474};
RA   Zheng W.-S., Lu D.-C., Du Z.-J.;
RT   "Spiribacter halobius sp. nov., a moderately halophilic bacterium isolated
RT   from marine solar saltern.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWG63471.1}.
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DR   EMBL; QFFI01000010; PWG63471.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U2N2M1; -.
DR   OrthoDB; 9809920at2; -.
DR   Proteomes; UP000245474; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR046825; PDH_C.
DR   InterPro; IPR046826; PDH_N.
DR   InterPro; IPR003099; Prephen_DH.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF20463; PDH_C; 1.
DR   Pfam; PF02153; PDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245474}.
FT   DOMAIN          8..294
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
FT   COILED          245..272
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   294 AA;  30926 MW;  6AD536D1D95D1DA2 CRC64;
     MLSGVVIERL CIAGVGLIGG SLALALRAAG AVGEVVGTGR RSEPLERALA LGVLDRYELE
     PARAAEGADV VLLGVPLGAM RPVLAALRPG LGEGTVITDV GSAKGCVVAD AEAVFGALPA
     RFVPAHPIAG TEKSGVEAAF PTLFRGRRVI LTPDRHTDGE ALATVRGLWS AAGAEVVEMG
     VTAHDRMLAG TSHLPHLLAF GLVDMLARSP DHDEIFQYAA GGFRDFTRIA SSDPVMWRDV
     CLGNREALLA ALAAYREDLE RLTAMVAAAD GDALEAVFRN AKRTRDRHLH IFEK
//