ID A0A2U2PE01_9SPHI Unreviewed; 637 AA.
AC A0A2U2PE01;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN Name=acs {ECO:0000313|EMBL:PWG79616.1};
GN ORFNames=DDR33_16255 {ECO:0000313|EMBL:PWG79616.1};
OS Pararcticibacter amylolyticus.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pararcticibacter.
OX NCBI_TaxID=2173175 {ECO:0000313|EMBL:PWG79616.1, ECO:0000313|Proteomes:UP000245647};
RN [1] {ECO:0000313|EMBL:PWG79616.1, ECO:0000313|Proteomes:UP000245647}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FJ4-8 {ECO:0000313|EMBL:PWG79616.1,
RC ECO:0000313|Proteomes:UP000245647};
RA Cai Y.;
RT "Pedobacter chongqingensis sp. nov., isolated from a rottenly hemp rope.";
RL Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWG79616.1}.
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DR EMBL; QEAS01000013; PWG79616.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U2PE01; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000245647; Unassembled WGS sequence.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:PWG79616.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000245647}.
FT DOMAIN 11..66
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 68..458
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 520..599
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 637 AA; 70882 MW; 9D07BE58F94E4398 CRC64;
MNLKISSFDE YKEVYNYSVK DPEKFWGEVA DNFYWRKKWD KVLKWNFRDP EIVWFEGAKL
NITENCLDRH LEQNGDTAAI IWESNDPDEA HRVLTYRQLH DKVCQFANVL KNNGVKKGDR
VCIYLPMVPE LAIAVLACAR IGAIHSVIFG GFSAQSIADR INDAECCVVI TADGGFRGAK
DIPLKEVIDD ALVQCRSVNK VIVLTRSRTP VSMIKGRDVW WEDEIKKVET QGNPECPPEE
MDAEDVLFIL YTSGSTGKPK GVVHTCGGYM VYTGYTFANV FQYEPGEIYF CTADIGWITG
HSYIVYGPLS QGATTLMFEG VPTWPGPDRL WQITDKFKVN ILYTAPTAIR SLMGFGDEPL
EGKDLSSLKK LGSVGEPINE EAWHWFHDKV GKGNCPIADT WWQTETGGLM ISPIAGITPL
KPGYASLPLP GIQPCLMDEN AKEIEGNGVS GNLCIKFPWP GMLRTTYGDH ERCRNTYFSA
YPDMYFTGDG CLRDDDGFYR ITGRVDDVLN VSGHRIGTAE VENAINMHAD VVESAVVGYP
HAIKGQGIYA YVILGSSLHN EAELVQKDIL KTVTRIIGAI AKPDKIQFVT GLPKTRSGKI
MRRILRKIAE GDTSNLGDTS TLLDPGVVEE IRSGALV
//
