ID   A0A2U2RHT4_9MICO        Unreviewed;       339 AA.
AC   A0A2U2RHT4;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN   ORFNames=DEO23_12555 {ECO:0000313|EMBL:PWH05408.1};
OS   Brachybacterium endophyticum.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermabacteraceae;
OC   Brachybacterium.
OX   NCBI_TaxID=2182385 {ECO:0000313|EMBL:PWH05408.1, ECO:0000313|Proteomes:UP000245590};
RN   [1] {ECO:0000313|EMBL:PWH05408.1, ECO:0000313|Proteomes:UP000245590}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M1HQ-2 {ECO:0000313|EMBL:PWH05408.1,
RC   ECO:0000313|Proteomes:UP000245590};
RA   Tuo L.;
RT   "Brachybacterium sp. M1HQ-2T, whole genome shotgun sequence.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWH05408.1}.
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DR   EMBL; QFKX01000005; PWH05408.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U2RHT4; -.
DR   OrthoDB; 9814325at2; -.
DR   Proteomes; UP000245590; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF13519; VWA_2; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245590};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        40..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        294..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          69..275
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          216..241
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   339 AA;  37630 MW;  A9F83F9EACEFEACA CRC64;
     MHLEHLIPLW ATILIFVPLL ALAVVMMVRR PRQRWAWVRR ALMVALLAVI ALRPATYTET
     EQTQRMNANV FFVVDRTGSM NAEDYADGTP RLDGVERDMD RVMSMTKGSR YSIISFDSTA
     ASQLPLTTDA GAAQAWIDTL STEPTAHSKG SNVDRPLDTL TEAVSDARTD DPDSQVLVYF
     LSDGENTDGK DSQSFDQLKP MVDAGGVLGY GTPQGGPMRA SGAGTDGEYI TDSSGKKGTS
     RIDEKQLQTI ADQLGVPYLH RTDPEAAIEG TMDGIDLKPV PIESRRDVAS FRDWYWIAAI
     PLACLFIWEL GEMTYRLPRR RDRRELTSVR ERAGEGDLR
//