ID   A0A2U2RMR5_9MICO        Unreviewed;       353 AA.
AC   A0A2U2RMR5;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=CoA ester lyase {ECO:0000313|EMBL:PWH07170.1};
GN   ORFNames=DEO23_00445 {ECO:0000313|EMBL:PWH07170.1};
OS   Brachybacterium endophyticum.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Dermabacteraceae;
OC   Brachybacterium.
OX   NCBI_TaxID=2182385 {ECO:0000313|EMBL:PWH07170.1, ECO:0000313|Proteomes:UP000245590};
RN   [1] {ECO:0000313|EMBL:PWH07170.1, ECO:0000313|Proteomes:UP000245590}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M1HQ-2 {ECO:0000313|EMBL:PWH07170.1,
RC   ECO:0000313|Proteomes:UP000245590};
RA   Tuo L.;
RT   "Brachybacterium sp. M1HQ-2T, whole genome shotgun sequence.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWH07170.1}.
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DR   EMBL; QFKX01000001; PWH07170.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U2RMR5; -.
DR   OrthoDB; 4322898at2; -.
DR   Proteomes; UP000245590; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR   InterPro; IPR005000; Aldolase/citrate-lyase_domain.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR   PANTHER; PTHR32308:SF10; CITRATE LYASE SUBUNIT BETA; 1.
DR   PANTHER; PTHR32308; LYASE BETA SUBUNIT, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G13030)-RELATED; 1.
DR   Pfam; PF03328; HpcH_HpaI; 1.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:PWH07170.1};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245590}.
FT   DOMAIN          90..289
FT                   /note="HpcH/HpaI aldolase/citrate lyase"
FT                   /evidence="ECO:0000259|Pfam:PF03328"
FT   REGION          14..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   353 AA;  37523 MW;  825B2892BFCE3AAE CRC64;
     MRCSARWPWW ASADAPSTAD CDGPGGIQSG RDLRGAGVGG VRARVAPVVA SGRTRRRRTG
     PALRGVVSGP SQARTVGGPP VTHVPAEISR SWLLVSGRHS EQFDRAVRTR ADQVVLDIED
     AVDPQHKAEA RGDVVRWLED GSAWVRINDR SSPFWEEDVD ALAEVSGLEG VVLAKAEAPE
     QVTETAERLG GSTPVIALVE SALGIEEAVS IARARGAFRL AFGSGDYRRD TGTSSDDLAM
     AYPRSRLVVA SRIGDLPGPI DGPTVGSSHP ILREQSTTAV SLGMTGKLCL DIDQLSVINE
     TISPTPSDVE WARDFLADFA DRGGVIRDGS DLPRLGRARK IEHLASAFGI DPA
//