ID A0A2U2XEH8_9FLAO Unreviewed; 319 AA.
AC A0A2U2XEH8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Arginase {ECO:0000256|ARBA:ARBA00018123};
DE EC=3.5.3.1 {ECO:0000256|ARBA:ARBA00012168};
GN ORFNames=DIT68_06225 {ECO:0000313|EMBL:PWH86147.1};
OS Brumimicrobium oceani.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Crocinitomicaceae; Brumimicrobium.
OX NCBI_TaxID=2100725 {ECO:0000313|EMBL:PWH86147.1, ECO:0000313|Proteomes:UP000245370};
RN [1] {ECO:0000313|EMBL:PWH86147.1, ECO:0000313|Proteomes:UP000245370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C305 {ECO:0000313|EMBL:PWH86147.1,
RC ECO:0000313|Proteomes:UP000245370};
RA Kou Y.;
RT "Brumimicrobium oceani sp. nov., isolated from coastal sediment.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PWH86147.1, ECO:0000313|Proteomes:UP000245370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C305 {ECO:0000313|EMBL:PWH86147.1,
RC ECO:0000313|Proteomes:UP000245370};
RA Lanie J.A., Ng W.-L., Kazmierczak K.M., Andrzejewski T.M., Davidsen T.M.,
RA Wayne K.J., Tettelin H., Glass J.I., Rusch D., Podicherti R., Tsui H.-C.T.,
RA Winkler M.E.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + L-arginine = L-ornithine + urea; Xref=Rhea:RHEA:20569,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:16199, ChEBI:CHEBI:32682,
CC ChEBI:CHEBI:46911; EC=3.5.3.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000227};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- PATHWAY: Nitrogen metabolism; urea cycle; L-ornithine and urea from L-
CC arginine: step 1/1. {ECO:0000256|ARBA:ARBA00005098}.
CC -!- SIMILARITY: Belongs to the arginase family. {ECO:0000256|PROSITE-
CC ProRule:PRU00742}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWH86147.1}.
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DR EMBL; QFRJ01000003; PWH86147.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U2XEH8; -.
DR OrthoDB; 9788689at2; -.
DR Proteomes; UP000245370; Unassembled WGS sequence.
DR GO; GO:0004053; F:arginase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.
DR CDD; cd09989; Arginase; 1.
DR Gene3D; 3.40.800.10; Ureohydrolase domain; 1.
DR InterPro; IPR014033; Arginase.
DR InterPro; IPR006035; Ureohydrolase.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR43782; ARGINASE; 1.
DR PANTHER; PTHR43782:SF3; ARGINASE; 1.
DR Pfam; PF00491; Arginase; 1.
DR PIRSF; PIRSF036979; Arginase; 2.
DR PRINTS; PR00116; ARGINASE.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
DR PROSITE; PS51409; ARGINASE_2; 1.
PE 3: Inferred from homology;
KW Arginine metabolism {ECO:0000256|ARBA:ARBA00022503};
KW Reference proteome {ECO:0000313|Proteomes:UP000245370}.
SQ SEQUENCE 319 AA; 35186 MW; A5C953A603CF0C56 CRC64;
MAKSIAYIIN DSEISAGTRG ASLGPGAMRV ADDNSGNFLF SKYPIHYVKT MNHLLDQPTK
YKWGKRADGL ATVYKNVAEV VSRERKKNDF IIVVAGDHGS AGGTIAGLKV ANPQHRLGVL
WIDAHGDLHT PYTTPSGNMH GMPLATALNE DNLESKQNDP VPDTIKFWNE LKNTGGIAPK
IEAQDLGFIG LRDLETPEVE LMERKGIKNI SVDEIRTEGV QKIIDRLEEK YADCDELYIS
FDVDSMDPDI VSHGTGTPVP NGLTPNEASE LLRHYAAHPK VKCIEFVEVN PCLDEKTNHM
AEVAYYLMKE VVEVAEKKA
//
