ID A0A2U2XFH7_9FLAO Unreviewed; 361 AA.
AC A0A2U2XFH7;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Peptide chain release factor 1 {ECO:0000256|HAMAP-Rule:MF_00093};
DE Short=RF-1 {ECO:0000256|HAMAP-Rule:MF_00093};
GN Name=prfA {ECO:0000256|HAMAP-Rule:MF_00093,
GN ECO:0000313|EMBL:PWH86461.1};
GN ORFNames=DIT68_04280 {ECO:0000313|EMBL:PWH86461.1};
OS Brumimicrobium oceani.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Crocinitomicaceae; Brumimicrobium.
OX NCBI_TaxID=2100725 {ECO:0000313|EMBL:PWH86461.1, ECO:0000313|Proteomes:UP000245370};
RN [1] {ECO:0000313|EMBL:PWH86461.1, ECO:0000313|Proteomes:UP000245370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C305 {ECO:0000313|EMBL:PWH86461.1,
RC ECO:0000313|Proteomes:UP000245370};
RA Kou Y.;
RT "Brumimicrobium oceani sp. nov., isolated from coastal sediment.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PWH86461.1, ECO:0000313|Proteomes:UP000245370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C305 {ECO:0000313|EMBL:PWH86461.1,
RC ECO:0000313|Proteomes:UP000245370};
RA Lanie J.A., Ng W.-L., Kazmierczak K.M., Andrzejewski T.M., Davidsen T.M.,
RA Wayne K.J., Tettelin H., Glass J.I., Rusch D., Podicherti R., Tsui H.-C.T.,
RA Winkler M.E.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Peptide chain release factor 1 directs the termination of
CC translation in response to the peptide chain termination codons UAG and
CC UAA. {ECO:0000256|ARBA:ARBA00002986, ECO:0000256|HAMAP-Rule:MF_00093}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00093}.
CC -!- PTM: Methylated by PrmC. Methylation increases the termination
CC efficiency of RF1. {ECO:0000256|HAMAP-Rule:MF_00093}.
CC -!- SIMILARITY: Belongs to the prokaryotic/mitochondrial release factor
CC family. {ECO:0000256|ARBA:ARBA00010835, ECO:0000256|HAMAP-
CC Rule:MF_00093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWH86461.1}.
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DR EMBL; QFRJ01000002; PWH86461.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U2XFH7; -.
DR OrthoDB; 9806673at2; -.
DR Proteomes; UP000245370; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016149; F:translation release factor activity, codon specific; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.160.20; -; 1.
DR Gene3D; 3.30.70.1660; -; 1.
DR Gene3D; 6.10.140.1950; -; 1.
DR HAMAP; MF_00093; Rel_fac_1; 1.
DR InterPro; IPR005139; PCRF.
DR InterPro; IPR000352; Pep_chain_release_fac_I.
DR InterPro; IPR045853; Pep_chain_release_fac_I_sf.
DR InterPro; IPR004373; RF-1.
DR NCBIfam; TIGR00019; prfA; 1.
DR PANTHER; PTHR43804; LD18447P; 1.
DR PANTHER; PTHR43804:SF7; LD18447P; 1.
DR Pfam; PF03462; PCRF; 1.
DR Pfam; PF00472; RF-1; 1.
DR SMART; SM00937; PCRF; 1.
DR SUPFAM; SSF75620; Release factor; 1.
DR PROSITE; PS00745; RF_PROK_I; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00093};
KW Methylation {ECO:0000256|ARBA:ARBA00022481, ECO:0000256|HAMAP-
KW Rule:MF_00093}; Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00093};
KW Reference proteome {ECO:0000313|Proteomes:UP000245370}.
FT DOMAIN 229..245
FT /note="Prokaryotic-type class I peptide chain release
FT factors"
FT /evidence="ECO:0000259|PROSITE:PS00745"
FT COILED 38..98
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 236
FT /note="N5-methylglutamine"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00093"
SQ SEQUENCE 361 AA; 41364 MW; 49221073E7A11A5C CRC64;
MDNTLLSKLE AIHYRFKEVG QLIVDPDIIS DMKRYVKLNK EYKDLEELDK VYQEYKNVLE
NIASSKELLA EEKDPEMREM AKMELDELET QRPEMEEEIK FMLIPKDPED DKNVIIELRS
GTGGDEACIF VEDIYRMYTM YFKEKGWKVE IINSNEGTTG YKEVSMNVEG EGVYGMMKFE
SGVHRVQRVP ETESQGRVHT SAITVAVLPE AEEVDVELNM GDVRRDTFRA SGAGGQHVNK
TDSAIRLTHA PSGIVVECQD GRSQHKNYDK ALSVLRSRLY QVELDKIMSE RAEKRKSLVS
SGDRSAKIRT YNYPQGRITD HRINKTMYNL SSFMNGDIQE MIDALKMAEN AEKLKGEEGI
A
//
