ID   A0A2U2Z315_9ACTN        Unreviewed;       513 AA.
AC   A0A2U2Z315;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=AMP-dependent acyl-CoA synthetase {ECO:0000313|EMBL:PWI06672.1};
GN   ORFNames=DIZ27_32415 {ECO:0000313|EMBL:PWI06672.1};
OS   Streptomyces sp. NWU339.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2185284 {ECO:0000313|EMBL:PWI06672.1, ECO:0000313|Proteomes:UP000245372};
RN   [1] {ECO:0000313|EMBL:PWI06672.1, ECO:0000313|Proteomes:UP000245372}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NWU339 {ECO:0000313|EMBL:PWI06672.1,
RC   ECO:0000313|Proteomes:UP000245372};
RA   Adegboye M.F., Lobb B., Babalola O., Doxey A.C., Ma K.;
RT   "Draft genomes of two novel cellulolytic Streptomyces strains isolated from
RT   South African rhizosphere soils.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWI06672.1}.
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DR   EMBL; QFRK01000038; PWI06672.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U2Z315; -.
DR   OrthoDB; 9803968at2; -.
DR   Proteomes; UP000245372; Unassembled WGS sequence.
DR   GO; GO:0016877; F:ligase activity, forming carbon-sulfur bonds; IEA:UniProt.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000245372}.
FT   DOMAIN          10..362
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          412..488
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   513 AA;  55089 MW;  AF33BF0611DA6820 CRC64;
     MNINDLVRYW GKSRPDHAAI IFGDDVQSWA ELDAVSDALA RGLAARGVRK GDRVGVLMRN
     RPELAHVILA TLKLGAISVP LNFRLLASEL APLLQDADPR VVVTEGELAP LLEPGHKALG
     FEIFATDSSD LPGYNLLMAE SGTVPITEVD EDDGAFICYT SGTTGVQKGA LLTHRSVLAP
     GQAQVITHGI SWRDRVLLAA PLVYTGSVIS VFMQLVVYPG ATMVLPGDFD AERCLDALER
     HQVTATTTVP VVWERMAALP GFGRRRLADF KFAGAGGAPV NPELLKVYQA RGIPVTQVYG
     LTEASGLVST MRYEDALTRP GFAGLPLVGT AIRIADSEGK TVPAGEVGEI LVRGSHTMHG
     YWNRPQETAE TLVDGWLRTG DLGLQDDGGF LKVVDRRKDV VISGGLNIYP AEIEKVLSSV
     EGVVDLAVIG VADDRWGEVP MIVFHTDQDP SVVARRLTST AQASLARYKQ PKHAVALAQP
     LPRTFSGKLA KPVLREQFTR TPSDAIALSP SSS
//