ID   A0A2U2Z581_9ACTN        Unreviewed;       437 AA.
AC   A0A2U2Z581;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   RecName: Full=Trk system potassium uptake protein TrkA {ECO:0000256|ARBA:ARBA00017378};
GN   ORFNames=DIZ27_28365 {ECO:0000313|EMBL:PWI07414.1};
OS   Streptomyces sp. NWU339.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2185284 {ECO:0000313|EMBL:PWI07414.1, ECO:0000313|Proteomes:UP000245372};
RN   [1] {ECO:0000313|EMBL:PWI07414.1, ECO:0000313|Proteomes:UP000245372}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NWU339 {ECO:0000313|EMBL:PWI07414.1,
RC   ECO:0000313|Proteomes:UP000245372};
RA   Adegboye M.F., Lobb B., Babalola O., Doxey A.C., Ma K.;
RT   "Draft genomes of two novel cellulolytic Streptomyces strains isolated from
RT   South African rhizosphere soils.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWI07414.1}.
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DR   EMBL; QFRK01000029; PWI07414.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U2Z581; -.
DR   OrthoDB; 9775180at2; -.
DR   Proteomes; UP000245372; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR   InterPro; IPR006036; K_uptake_TrkA.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR003148; RCK_N.
DR   PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR   PANTHER; PTHR43833:SF5; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKA; 1.
DR   Pfam; PF02080; TrkA_C; 2.
DR   Pfam; PF02254; TrkA_N; 2.
DR   PRINTS; PR00335; KUPTAKETRKA.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR   SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR   PROSITE; PS51202; RCK_C; 2.
DR   PROSITE; PS51201; RCK_N; 2.
PE   4: Predicted;
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245372}.
FT   DOMAIN          2..125
FT                   /note="RCK N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51201"
FT   DOMAIN          137..220
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51202"
FT   DOMAIN          226..349
FT                   /note="RCK N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51201"
FT   DOMAIN          361..437
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51202"
SQ   SEQUENCE   437 AA;  46600 MW;  F8C135B9BBEA02C1 CRC64;
     MQVIVVGAGQ VGHTVVKSLA ETHECTVIDI DEARLEAVSH AYDVRITRGS GTWRETLLEA
     GVADAELVLA CTSRDEVNLV TAMLARRLSS ARTVVRATGM DYLEAWRAGD LDVDLLVSTA
     FETASAVARV LHVPGARHVD FFAGGEVVVL GVDIREARPP RFAGRPLRDA GLPAASRVVA
     VVRDGNWIRP TAHEVVRPGD WVIVMASLAA ARAWSRLVTG ADPVDDVALF GAGRMGTAIA
     RVLLDKGISV RLIEPDAARA RAAAAALDRA RVFHATGLDP AFLRRERVGA AGAAVFASGD
     DSRNLYAAVL AKVHGVELTL TVLEDPAAAE VFEAAGADVT IDPGDETAEK MARFTFDERT
     HQMAMLGDDR FEVLDITVRP DSRFAHGPVD ALPEAGVGAI VRDGTVFFPG GEDELRPGDR
     VIVLTEPDRV PTIEHDL
//