ID   A0A2U2ZG59_9ACTN        Unreviewed;       446 AA.
AC   A0A2U2ZG59;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Site-specific integrase {ECO:0000313|EMBL:PWI11278.1};
GN   ORFNames=DIZ27_07830 {ECO:0000313|EMBL:PWI11278.1};
OS   Streptomyces sp. NWU339.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2185284 {ECO:0000313|EMBL:PWI11278.1, ECO:0000313|Proteomes:UP000245372};
RN   [1] {ECO:0000313|EMBL:PWI11278.1, ECO:0000313|Proteomes:UP000245372}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NWU339 {ECO:0000313|EMBL:PWI11278.1,
RC   ECO:0000313|Proteomes:UP000245372};
RA   Adegboye M.F., Lobb B., Babalola O., Doxey A.C., Ma K.;
RT   "Draft genomes of two novel cellulolytic Streptomyces strains isolated from
RT   South African rhizosphere soils.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC       {ECO:0000256|ARBA:ARBA00008857}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWI11278.1}.
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DR   EMBL; QFRK01000004; PWI11278.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U2ZG59; -.
DR   OrthoDB; 1822491at2; -.
DR   Proteomes; UP000245372; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   CDD; cd01189; INT_ICEBs1_C_like; 1.
DR   Gene3D; 1.10.150.130; -; 1.
DR   Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR010998; Integrase_recombinase_N.
DR   InterPro; IPR004107; Integrase_SAM-like_N.
DR   PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR   PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR   Pfam; PF14659; Phage_int_SAM_3; 1.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   3: Inferred from homology;
KW   DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245372};
KW   Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT   DOMAIN          189..407
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000259|PROSITE:PS51898"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          408..446
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   446 AA;  49379 MW;  94014B9A613E7BD6 CRC64;
     MYDRWHKSHP KPDETQCGEH KSRTRRMVPT SDHGIGKRWQ VRYRDLDGHQ RKENFHTRAE
     ADKRAAEVDV EIRSGSYVVP AETKQTLGAY ARKWLDANSV GPTTALRYEA TVRNHIVAHL
     GRRELRSLNK PSVIQGWVRT LQDGGFEVST IEGIFDILSS ILGMAVEDGL LPKNPCKAKS
     VKLPTATKKK IIPWPMERVR AVIAGLPKRF QAGGKLAFGC GLRQGEVFGF AVEDIDFKGG
     WIHVNRQVRL VGTKPVFALP KGNKIRSVPL PAQLAAVLKT HMKEFPPVEV TLPWAKPDGE
     PKTFRLLFVD EKHRAYNRSV FNMGAWKLAL AAAGVIPPRE RGARYLQAAP DDGMHALRHA
     YASVLLDAGE SIKALSEYLG HSDPGFTLRT YTHLLPSSET RTRKAIDDAF TEAEEAEAED
     DGAPPAAQGT SEPPAKPMCP QCALAA
//