ID   A0A2U3C1G8_9ACTN        Unreviewed;       365 AA.
AC   A0A2U3C1G8;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=PPM-type phosphatase domain-containing protein {ECO:0000259|SMART:SM00331};
GN   ORFNames=CK485_11495 {ECO:0000313|EMBL:PWI42881.1};
OS   Streptomyces sp. ICBB 8177.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=563922 {ECO:0000313|EMBL:PWI42881.1, ECO:0000313|Proteomes:UP000245673};
RN   [1] {ECO:0000313|EMBL:PWI42881.1, ECO:0000313|Proteomes:UP000245673}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ICBB 8177 {ECO:0000313|EMBL:PWI42881.1,
RC   ECO:0000313|Proteomes:UP000245673};
RX   PubMed=29773836; DOI=10.1038/s41598-018-26179-w;
RA   Pavlikova M., Kamenik Z., Janata J., Kadlcik S., Kuzma M., Najmanova L.;
RT   "Novel pathway of 3-hydroxyanthranilic acid formation in limazepine
RT   biosynthesis reveals evolutionary relation between phenazines and
RT   pyrrolobenzodiazepines.";
RL   Sci. Rep. 8:7810-7810(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PWI42881.1}.
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DR   EMBL; NSKH01000018; PWI42881.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U3C1G8; -.
DR   OrthoDB; 342342at2; -.
DR   Proteomes; UP000245673; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245673};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        41..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          135..358
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
SQ   SEQUENCE   365 AA;  37584 MW;  A1DF7006311A4926 CRC64;
     MATFPGRWPR YVGFVPAALA AGGLVWNALS PSEYWGDGMV AAACVVAGAL TSLRYTVLVG
     TVITLGIIAL IARDGYVGHT SGSLELANTV FAALVGVAVN LIIARHGHRL AVVRSVAEAA
     QAAVLPAPPA RVGPLAVAAC YQAAQTEALI GGDAYAVQPS RYGPRLLIAD VRGKGLGAVR
     AVSVLLGAFR ENADRAPDLV TLADRLEQSL LRELVGRERD EVGLEGFVTA LLGEFSPRGD
     TLRLLDCGHP AAYLFGDGGL KALESADPGL PLGMSVLGVA RPAPDCWPVA VGDTLLLVTD
     GVTEARNGAG VFYDPMTELA GAGPFRSPGD ALDAVLSGVR RWTGGPRDDD MALLAVTRVP
     GPPAA
//