ID A0A2U3C7X9_9ACTN Unreviewed; 317 AA.
AC A0A2U3C7X9;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Aspartate aminotransferase {ECO:0000313|EMBL:PWI45150.1};
GN ORFNames=CK485_03030 {ECO:0000313|EMBL:PWI45150.1};
OS Streptomyces sp. ICBB 8177.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=563922 {ECO:0000313|EMBL:PWI45150.1, ECO:0000313|Proteomes:UP000245673};
RN [1] {ECO:0000313|EMBL:PWI45150.1, ECO:0000313|Proteomes:UP000245673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ICBB 8177 {ECO:0000313|EMBL:PWI45150.1,
RC ECO:0000313|Proteomes:UP000245673};
RX PubMed=29773836; DOI=10.1038/s41598-018-26179-w;
RA Pavlikova M., Kamenik Z., Janata J., Kadlcik S., Kuzma M., Najmanova L.;
RT "Novel pathway of 3-hydroxyanthranilic acid formation in limazepine
RT biosynthesis reveals evolutionary relation between phenazines and
RT pyrrolobenzodiazepines.";
RL Sci. Rep. 8:7810-7810(2018).
CC -!- SIMILARITY: Belongs to the DegT/DnrJ/EryC1 family.
CC {ECO:0000256|RuleBase:RU004508}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PWI45150.1}.
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DR EMBL; NSKH01000003; PWI45150.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2U3C7X9; -.
DR OrthoDB; 9804264at2; -.
DR Proteomes; UP000245673; Unassembled WGS sequence.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000653; DegT/StrS_aminotransferase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR30244:SF36; 3-OXO-GLUCOSE-6-PHOSPHATE:GLUTAMATE AMINOTRANSFERASE; 1.
DR PANTHER; PTHR30244; TRANSAMINASE; 1.
DR Pfam; PF01041; DegT_DnrJ_EryC1; 2.
DR PIRSF; PIRSF000390; PLP_StrS; 2.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:PWI45150.1};
KW Antibiotic biosynthesis {ECO:0000256|ARBA:ARBA00023194};
KW Pyridoxal phosphate {ECO:0000256|RuleBase:RU004508};
KW Reference proteome {ECO:0000313|Proteomes:UP000245673};
KW Transferase {ECO:0000313|EMBL:PWI45150.1}.
SQ SEQUENCE 317 AA; 33007 MW; 5A426DB7FF634259 CRC64;
MKPSGSVIEG SLVAAFEREV AELVGGRICV AVDEGRSALA LALSALGVAR GDEVVVPSYA
PVGAADAIRL VGAVPVFADI DPVTYCLDPE AVAAVLSPRT VAVVAAHQFG HPAAMRELGE
LAERHGVALL EYASRAYGAA LDGQLVGTFG LMAVFGFGVA TQDAELARRL RGLRTGDAVP
AEESAAVARG ELERVAGFTA RRRANARVFD SALTGVLPPH AAEGTRHVYQ RYVVRVPGNG
RPDRDAFAKA LAARGVDAAV PVTTPVHRLP AYRSGAHLPH TERAAAETLS LPVHPMLTER
EVERVVQACN ALGGLLG
//
