ID A0A2U3P441_9MYCO Unreviewed; 375 AA.
AC A0A2U3P441;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Inosine 5-monophosphate dehydrogenase {ECO:0000313|EMBL:SPM38508.1};
GN ORFNames=MNAB215_685 {ECO:0000313|EMBL:SPM38508.1};
OS Mycobacterium numidiamassiliense.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1841861 {ECO:0000313|EMBL:SPM38508.1, ECO:0000313|Proteomes:UP000240424};
RN [1] {ECO:0000313|EMBL:SPM38508.1, ECO:0000313|Proteomes:UP000240424}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AB215 {ECO:0000313|EMBL:SPM38508.1,
RC ECO:0000313|Proteomes:UP000240424};
RG Urmite Genomes;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the IMPDH/GMPR family.
CC {ECO:0000256|ARBA:ARBA00005502}.
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DR EMBL; FUEZ01000003; SPM38508.1; -; Genomic_DNA.
DR RefSeq; WP_077078380.1; NZ_FUEZ01000003.1.
DR AlphaFoldDB; A0A2U3P441; -.
DR STRING; 1841861.GCA_900157365_04888; -.
DR OrthoDB; 9805398at2; -.
DR Proteomes; UP000240424; Unassembled WGS sequence.
DR GO; GO:0003938; F:IMP dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR005990; IMP_DH.
DR InterPro; IPR005992; IMP_DH-rel2.
DR InterPro; IPR001093; IMP_DH_GMPRt.
DR NCBIfam; TIGR01304; IMP_DH_rel_2; 1.
DR PANTHER; PTHR11911:SF111; INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11911; INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; 1.
DR Pfam; PF00478; IMPDH; 1.
DR SMART; SM01240; IMPDH; 1.
DR SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000240424}.
FT DOMAIN 17..301
FT /note="IMP dehydrogenase/GMP reductase"
FT /evidence="ECO:0000259|Pfam:PF00478"
SQ SEQUENCE 375 AA; 39217 MW; 3BC1C48CF9C5ED12 CRC64;
MVEIGMGRVA RRTFELSEIS IVPSRRTRSS QDVSTTWQLD AYRFEIPVVA HPTDALVSPE
FAIELGRLGG LGVLNGEGLI GRHADVGAKI AQLLEAAEKE PEPSASIRLL QELHAAPLNP
DLLGAAVARI REAGVTTAVR VSPQNAQALT PVLLQAGIDL LVIQGTIVSA ERVDSHGEPL
NLKTFISELD VPVVAGGVLD HRTALHLMRT GAAGVIVGYG STRGVTTSDE VLGISVPMAT
AIADAAAARR EYLDETGGRY VHVLADGDIH TSGELAKAIA CGADAVVLGT PLAESAEALG
DGWFWPTAAA HPSLPRGALL QIAVGERPPL EQILNGPSDD PFGSLNLVGG LRRSMAKAGY
CDLKEFQKVG LTVGS
//
