ID   A0A2U3P8A9_9MYCO        Unreviewed;       400 AA.
AC   A0A2U3P8A9;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Serine protease {ECO:0000313|EMBL:SPM39989.1};
GN   ORFNames=MNAB215_2184 {ECO:0000313|EMBL:SPM39989.1};
OS   Mycobacterium numidiamassiliense.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=1841861 {ECO:0000313|EMBL:SPM39989.1, ECO:0000313|Proteomes:UP000240424};
RN   [1] {ECO:0000313|EMBL:SPM39989.1, ECO:0000313|Proteomes:UP000240424}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AB215 {ECO:0000313|EMBL:SPM39989.1,
RC   ECO:0000313|Proteomes:UP000240424};
RG   Urmite Genomes;
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FUEZ01000004; SPM39989.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2U3P8A9; -.
DR   STRING; 1841861.GCA_900157365_00501; -.
DR   Proteomes; UP000240424; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   GO; GO:0009403; P:toxin biosynthetic process; IEA:InterPro.
DR   Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR   InterPro; IPR003825; Colicin-V_CvpA.
DR   InterPro; IPR047680; MarP-like.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   InterPro; IPR001940; Peptidase_S1C.
DR   NCBIfam; NF033740; MarP_fam_protase; 1.
DR   PANTHER; PTHR43019; SERINE ENDOPROTEASE DEGS; 1.
DR   PANTHER; PTHR43019:SF36; SERINE PROTEASE RV3671C; 1.
DR   Pfam; PF02674; Colicin_V; 1.
DR   Pfam; PF13365; Trypsin_2; 1.
DR   PRINTS; PR00834; PROTEASES2C.
DR   SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:SPM39989.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Protease {ECO:0000313|EMBL:SPM39989.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000240424};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        33..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        66..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        102..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   400 AA;  41019 MW;  822140A530FF9B80 CRC64;
     MNSMTPSQWL DVAVLAVAFI AAISGWRSGA VGSLFSFIGV LLGAIAGVLL APHIVSHIAA
     PRAKLFTALF LILALVVVGE VAGVVLGRAV RGAIHSRTIR TIDSVIGVGV QLVVVLTAAW
     LLATPLTQSK DQPELAAAVR GSQVLARVNE VAPPWLKTVP KRLSALLNTS GLPAVLEPFS
     RTPVIPVASP DPALATNPVV MSVAPSVVKV RSVAPSCQKV LEGSGFVIAP DRVMTNAHVV
     AGSSSVQVYA SGNPLDATVV SYDPSVDIAI LAVPNLPPQP LAFAENEAKS AADVVVLGYP
     GGGNFTATPA RIREAIKLSG PDIYRDPAPV TRDVYTIRAN VEQGNSGGPL IDMSGHVLGV
     VFGAAVDDPD TGFVLTAGEV SGQLSRIGDT QQVGTGACVS
//