ID A0A2U3UZD8_TURTR Unreviewed; 439 AA.
AC A0A2U3UZD8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 07-OCT-2020, sequence version 2.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Forkhead box protein F2 {ECO:0000313|RefSeq:XP_004311990.3};
GN Name=FOXF2 {ECO:0000313|RefSeq:XP_004311990.3};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_004311990.3};
RN [1] {ECO:0000313|RefSeq:XP_004311990.3}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_004311990.3};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR RefSeq; XP_004311990.3; XM_004311942.3.
DR AlphaFoldDB; A0A2U3UZD8; -.
DR STRING; 9739.ENSTTRP00000005462; -.
DR InParanoid; A0A2U3UZD8; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000245320; Chromosome 10.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd20049; FH_FOXF1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46262; FORKHEAD BOX PROTEIN BINIOU; 1.
DR PANTHER; PTHR46262:SF3; FORKHEAD BOX PROTEIN F2; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Reference proteome {ECO:0000313|Proteomes:UP000245320}.
FT DOMAIN 92..186
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 92..186
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 48..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 249..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 330..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 439 AA; 45277 MW; FE3B7EFB95E80711 CRC64;
MTSEGGPPPA PLRRARSPGP GALQAALMSP PPAAAAAAAA LEAASSSSSS ASSSGAAGAA
PNACKSAGGG GGAGGSGAGA KKASSGLRRP EKPPYSYIAL IVMAIQSSPA KRLTLSEIYQ
FLQARFPFFR GAYQGWKNSV RHNLSLNECF IKLPKGLGRP GKGHYWTIDP ASEFMFEEGS
FRRRPRGFRR KCQALKPMYH RVVSGLGFGA SLLPQGFDFQ APPSAPLGCH GQGGYGGLDM
MPAGYDAGAG APGHAHPHHH HHHHVPHMSP NPGSTYMASC PVPAGPGGVG AAGGGGGGGG
DYGPDSSSSP VPSSPAVASA IECHSPYTSP AAHWSSPGAS PYLKQPPALT PGGTPAAPAG
LHTSMSTYSL EQSYLHQNAR EDLPVGLPRY QHHSTPVCDR KDFVLSFNSV SSFHPSASGP
YYHHHHHQSV CQDIKPCVM
//
