ID A0A2U3V066_TURTR Unreviewed; 93 AA.
AC A0A2U3V066;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=C-C motif chemokine {ECO:0000256|RuleBase:RU361150};
GN Name=CCL22 {ECO:0000313|RefSeq:XP_004313270.1};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_004313270.1};
RN [1] {ECO:0000313|RefSeq:XP_004313270.1}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_004313270.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU361150}.
CC -!- SIMILARITY: Belongs to the intercrine beta (chemokine CC) family.
CC {ECO:0000256|ARBA:ARBA00010868, ECO:0000256|RuleBase:RU361150}.
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DR RefSeq; XP_004313270.1; XM_004313222.3.
DR AlphaFoldDB; A0A2U3V066; -.
DR STRING; 9739.ENSTTRP00000009528; -.
DR Ensembl; ENSTTRT00000010046; ENSTTRP00000009528; ENSTTRG00000010047.
DR GeneID; 101323189; -.
DR InParanoid; A0A2U3V066; -.
DR OMA; RDYIRHP; -.
DR OrthoDB; 4265193at2759; -.
DR Proteomes; UP000245320; Chromosome 19.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR GO; GO:0008009; F:chemokine activity; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR CDD; cd00272; Chemokine_CC; 1.
DR Gene3D; 2.40.50.40; -; 1.
DR InterPro; IPR039809; Chemokine_b/g/d.
DR InterPro; IPR000827; Chemokine_CC_CS.
DR InterPro; IPR001811; Chemokine_IL8-like_dom.
DR InterPro; IPR036048; Interleukin_8-like_sf.
DR PANTHER; PTHR12015:SF102; C-C MOTIF CHEMOKINE 22; 1.
DR PANTHER; PTHR12015; SMALL INDUCIBLE CYTOKINE A; 1.
DR Pfam; PF00048; IL8; 1.
DR SMART; SM00199; SCY; 1.
DR SUPFAM; SSF54117; Interleukin 8-like chemokines; 1.
DR PROSITE; PS00472; SMALL_CYTOKINES_CC; 1.
PE 3: Inferred from homology;
KW Chemotaxis {ECO:0000256|RuleBase:RU361150};
KW Cytokine {ECO:0000256|ARBA:ARBA00022514, ECO:0000256|RuleBase:RU361150};
KW Reference proteome {ECO:0000313|Proteomes:UP000245320};
KW Secreted {ECO:0000256|RuleBase:RU361150};
KW Signal {ECO:0000256|RuleBase:RU361150}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|RuleBase:RU361150"
FT CHAIN 25..93
FT /note="C-C motif chemokine"
FT /evidence="ECO:0000256|RuleBase:RU361150"
FT /id="PRO_5015372216"
FT DOMAIN 33..91
FT /note="Chemokine interleukin-8-like"
FT /evidence="ECO:0000259|SMART:SM00199"
SQ SEQUENCE 93 AA; 10671 MW; FF400345B0AEDAF1 CRC64;
MASLQTPLLA ALILLAMILQ ATEAGPYGAN VEDSICCRDY IRHPLPLRLV KYYYWTSESC
RRPGVVLLTV RDREICADPR LPWVKKILQR LDQ
//
