ID A0A2U3V0Y4_TURTR Unreviewed; 171 AA.
AC A0A2U3V0Y4;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=T-cell surface glycoprotein CD3 delta chain {ECO:0000256|ARBA:ARBA00014256};
DE AltName: Full=T-cell receptor T3 delta chain {ECO:0000256|ARBA:ARBA00030628};
GN Name=CD3D {ECO:0000313|RefSeq:XP_004314219.2};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_004314219.2};
RN [1] {ECO:0000313|RefSeq:XP_004314219.2}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_004314219.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
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DR RefSeq; XP_004314219.2; XM_004314171.3.
DR AlphaFoldDB; A0A2U3V0Y4; -.
DR STRING; 9739.ENSTTRP00000004007; -.
DR Ensembl; ENSTTRT00000004257; ENSTTRP00000004007; ENSTTRG00000004258.
DR GeneID; 101320520; -.
DR InParanoid; A0A2U3V0Y4; -.
DR OMA; YQPLRDH; -.
DR OrthoDB; 4266454at2759; -.
DR Proteomes; UP000245320; Chromosome 8.
DR GO; GO:0042105; C:alpha-beta T cell receptor complex; IEA:Ensembl.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0045059; P:positive thymic T cell selection; IEA:Ensembl.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 1.10.287.770; YojJ-like; 1.
DR InterPro; IPR015484; CD3_esu/gsu/dsu.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR032052; Ig_4.
DR InterPro; IPR003110; Phos_immunorcpt_sig_ITAM.
DR PANTHER; PTHR10570:SF5; T-CELL SURFACE GLYCOPROTEIN CD3 DELTA CHAIN; 1.
DR PANTHER; PTHR10570; T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN / DELTA CHAIN; 1.
DR Pfam; PF16680; Ig_4; 1.
DR Pfam; PF02189; ITAM; 1.
DR SMART; SM00077; ITAM; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS51055; ITAM_1; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000245320};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..171
FT /note="T-cell surface glycoprotein CD3 delta chain"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015494898"
FT TRANSMEM 104..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 30..99
FT /note="CD3 gamma/delta subunit Ig-like"
FT /evidence="ECO:0000259|Pfam:PF16680"
SQ SEQUENCE 171 AA; 19054 MW; 36C356767DC55504 CRC64;
MEHRSFLSGL ILAALLSQVS PFDISVEELE DRVFLRCNES ITWLEGTVGK LAVDNKTMDL
GKRSLDPRGL YVCNKADGQT SKTPTLQVYY RMCQNCVELD SATLAGIVIT DIIATVLLAL
GIYCFAGHET GRLSRVADTQ VLLGNDQLYQ PLRDRNDAQY SHLGENWARN K
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