ID A0A2U3V3C8_TURTR Unreviewed; 367 AA.
AC A0A2U3V3C8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Alpha-2-HS-glycoprotein {ECO:0000256|ARBA:ARBA00019375};
DE AltName: Full=Fetuin-A {ECO:0000256|ARBA:ARBA00032001};
GN Name=AHSG {ECO:0000313|RefSeq:XP_004318275.1};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_004318275.1};
RN [1] {ECO:0000313|RefSeq:XP_004318275.1}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_004318275.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR RefSeq; XP_004318275.1; XM_004318227.3.
DR AlphaFoldDB; A0A2U3V3C8; -.
DR STRING; 9739.ENSTTRP00000015958; -.
DR GeneID; 101338172; -.
DR InParanoid; A0A2U3V3C8; -.
DR OrthoDB; 5312104at2759; -.
DR Proteomes; UP000245320; Chromosome 4.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00042; CY; 2.
DR Gene3D; 3.10.450.10; -; 2.
DR InterPro; IPR000010; Cystatin_dom.
DR InterPro; IPR025760; Cystatin_Fetuin_A.
DR InterPro; IPR046350; Cystatin_sf.
DR InterPro; IPR001363; Prot_inh_fetuin_CS.
DR PANTHER; PTHR13814:SF6; ALPHA-2-HS-GLYCOPROTEIN; 1.
DR PANTHER; PTHR13814; FETUIN; 1.
DR Pfam; PF00031; Cystatin; 1.
DR SMART; SM00043; CY; 2.
DR SUPFAM; SSF54403; Cystatin/monellin; 2.
DR PROSITE; PS51529; CYSTATIN_FETUIN_A; 2.
DR PROSITE; PS01254; FETUIN_1; 1.
DR PROSITE; PS01255; FETUIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000245320};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..367
FT /note="Alpha-2-HS-glycoprotein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015495841"
FT DOMAIN 27..133
FT /note="Cystatin fetuin-A-type"
FT /evidence="ECO:0000259|PROSITE:PS51529"
FT DOMAIN 144..256
FT /note="Cystatin fetuin-A-type"
FT /evidence="ECO:0000259|PROSITE:PS51529"
FT REGION 255..286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 367 AA; 38792 MW; 0BD2E7F56C122085 CRC64;
MKCLVLLLCL AQLCACRSVP HGPIPGYREP ACDDPETEQA ALAAVDYINK HLPHGYKHIL
NQIESVKVWP RRPTGEVFDL EIDTLETTCH VLDPTPLANC SVRQLKEHAV EGDCDFNVLK
QDGEFSVLSA KCDSSPDSAE DVHKVCPDCP LLAPLNDSRV VHAVEAALAA FNAQKNGSYF
QLVEISRAQF VPLSASVTVE FAVAATDCVA KEVVDPAKCN LLAEKQYGFC KGTVTEKVAG
GEDVAVTCTV FQTQPVLPQP QPDGAEAGPL TAAPGSAGPA LSPAGQPAAS LVVGPRAVAA
PPMPPPEYPA HYDLRHAFSG VASVESASGE AFHVGKTPKV AQPSIPAPEG PVPVVRPCPG
RIRHFKV
//
