ID A0A2U3V854_TURTR Unreviewed; 261 AA.
AC A0A2U3V854;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Endoplasmic reticulum resident protein 29 {ECO:0000256|ARBA:ARBA00014173, ECO:0000256|PIRNR:PIRNR027352};
GN Name=ERP29 {ECO:0000313|RefSeq:XP_004326629.1};
OS Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Delphinidae; Tursiops.
OX NCBI_TaxID=9739 {ECO:0000313|Proteomes:UP000245320, ECO:0000313|RefSeq:XP_004326629.1};
RN [1] {ECO:0000313|RefSeq:XP_004326629.1}
RP IDENTIFICATION.
RC TISSUE=Spleen {ECO:0000313|RefSeq:XP_004326629.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Does not seem to be a disulfide isomerase.
CC {ECO:0000256|PIRNR:PIRNR027352}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|PIRNR:PIRNR027352}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum lumen
CC {ECO:0000256|PIRNR:PIRNR027352}. Melanosome
CC {ECO:0000256|PIRNR:PIRNR027352}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_004326629.1; XM_004326581.2.
DR AlphaFoldDB; A0A2U3V854; -.
DR STRING; 9739.ENSTTRP00000010229; -.
DR Ensembl; ENSTTRT00000010787; ENSTTRP00000010229; ENSTTRG00000010793.
DR GeneID; 101337239; -.
DR InParanoid; A0A2U3V854; -.
DR OMA; KYVLVKF; -.
DR OrthoDB; 5403558at2759; -.
DR Proteomes; UP000245320; Chromosome 13.
DR GO; GO:0009986; C:cell surface; IEA:Ensembl.
DR GO; GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
DR GO; GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
DR GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR GO; GO:0050709; P:negative regulation of protein secretion; IEA:Ensembl.
DR GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
DR GO; GO:0001934; P:positive regulation of protein phosphorylation; IEA:Ensembl.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR GO; GO:1902235; P:regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway; IEA:Ensembl.
DR CDD; cd00238; ERp29c; 1.
DR CDD; cd03007; PDI_a_ERp29_N; 1.
DR Gene3D; 1.20.1150.12; Endoplasmic reticulum resident protein 29, C-terminal domain; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR016855; ERp29.
DR InterPro; IPR011679; ERp29_C.
DR InterPro; IPR036356; ERp29_C_sf.
DR InterPro; IPR012883; ERp29_N.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR12211; ENDOPLASMIC RETICULUM PROTEIN ERP29; 1.
DR PANTHER; PTHR12211:SF0; ENDOPLASMIC RETICULUM RESIDENT PROTEIN 29; 1.
DR Pfam; PF07749; ERp29; 1.
DR Pfam; PF07912; ERp29_N; 1.
DR PIRSF; PIRSF027352; ER_p29; 1.
DR SUPFAM; SSF47933; ERP29 C domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 4: Predicted;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824,
KW ECO:0000256|PIRNR:PIRNR027352};
KW Reference proteome {ECO:0000313|Proteomes:UP000245320};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..261
FT /note="Endoplasmic reticulum resident protein 29"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015420825"
FT DOMAIN 33..155
FT /note="ERp29 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF07912"
FT DOMAIN 156..251
FT /note="Endoplasmic reticulum resident protein 29 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF07749"
SQ SEQUENCE 261 AA; 29088 MW; E46F90C90A3E5E52 CRC64;
MAAAVPRAAS LSQLFPLLLF LLLLSAPQGG SGLHTKGALP LDTITFYKVI PKSKFVLVKF
DTQYPYGEKQ DEFKRLAENS ASSDDLLVAE VGISDYGDKL NMELSEKYKL DKENYPVFYL
FRDGDFENPV LYSGAVKVGA IQRWLKGHGV YLGMPGCLPA YDTLAGEFIR ASGMEARQAL
LKQGQDNLAS VKEAEKKWAE QYLKIMGKIL DQGEDFPASE MTRITKLIEK NKMSDGKKEE
LQKSLNILTA FQKKGAEKQE L
//
