ID A0A2U3VD68_ODORO Unreviewed; 395 AA.
AC A0A2U3VD68;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Endophilin-B2 {ECO:0000256|ARBA:ARBA00040331};
DE AltName: Full=SH3 domain-containing GRB2-like protein B2 {ECO:0000256|ARBA:ARBA00042180};
GN Name=SH3GLB2 {ECO:0000313|RefSeq:XP_004392550.1};
OS Odobenus rosmarus divergens (Pacific walrus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC Odobenus.
OX NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004392550.1};
RN [1] {ECO:0000313|RefSeq:XP_004392550.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Homodimer, and heterodimer with SH3GLB1.
CC {ECO:0000256|ARBA:ARBA00038771}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the endophilin family.
CC {ECO:0000256|ARBA:ARBA00006697}.
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DR RefSeq; XP_004392550.1; XM_004392493.2.
DR AlphaFoldDB; A0A2U3VD68; -.
DR GeneID; 101379955; -.
DR KEGG; oro:101379955; -.
DR CTD; 56904; -.
DR OrthoDB; 3494067at2759; -.
DR Proteomes; UP000245340; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd07617; BAR_Endophilin_B2; 1.
DR CDD; cd11944; SH3_Endophilin_B2; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR035640; Endophilin_B2_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14167:SF68; ENDOPHILIN-B2; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000245340};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 24..287
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 335..395
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT COILED 207..234
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 395 AA; 43986 MW; 00829CA075CF19B2 CRC64;
MDFNMKKLAS DAGIFFTRAV QFTEEKFGQA EKTELDAHFE NLLARADSTK NWTEKILRQT
EVLLQPNPSA RVEEFLYEKL DRKVPSRVTN GELLAQYMAE AASELGPTTP YGKTLIKVAE
AEKRLGAAER DFIHTASINF LTPLRNFLEG DWKTISKERR LLQNRRLDLD ACKARLKKAK
AAEAKATTVP DFQETRPRNY ILSASASALW NDEVDKAEQE LRVAQTEFDR QAEVTRLLLE
GISSTHVNHL RCLHEFVESQ TTYYAQCYRH MLDLQKQLGR FPGTFVGTTE PASPPLSSTS
PTTAAATMPV GPSVAGLAPP GEAALCLEEV TPPASGTRKA RVLYDYEAAD SSELALLADE
LITVYSLPGM DPDWLIGERG NKKGKVPVTY LELLS
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