ID A0A2U3VDQ7_ODORO Unreviewed; 1490 AA.
AC A0A2U3VDQ7;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Calmodulin-regulated spectrin-associated protein 2 isoform X1 {ECO:0000313|RefSeq:XP_004392785.1};
GN Name=CAMSAP2 {ECO:0000313|RefSeq:XP_004392785.1};
OS Odobenus rosmarus divergens (Pacific walrus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC Odobenus.
OX NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004392785.1};
RN [1] {ECO:0000313|RefSeq:XP_004392785.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- DOMAIN: The CKK domain binds microtubules. {ECO:0000256|PROSITE-
CC ProRule:PRU00841}.
CC -!- SIMILARITY: Belongs to the CAMSAP1 family. {ECO:0000256|PROSITE-
CC ProRule:PRU00841}.
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DR RefSeq; XP_004392785.1; XM_004392728.2.
DR STRING; 9708.A0A2U3VDQ7; -.
DR GeneID; 101384099; -.
DR KEGG; oro:101384099; -.
DR CTD; 23271; -.
DR InParanoid; A0A2U3VDQ7; -.
DR OrthoDB; 2918432at2759; -.
DR Proteomes; UP000245340; Unplaced.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-UniRule.
DR GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0030507; F:spectrin binding; IEA:InterPro.
DR GO; GO:0031175; P:neuron projection development; IEA:InterPro.
DR Gene3D; 3.10.20.360; CKK domain; 1.
DR InterPro; IPR032940; CAMSAP.
DR InterPro; IPR022613; CAMSAP-like_CH_dom.
DR InterPro; IPR031372; CAMSAP_CC1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR038209; CKK_dom_sf.
DR InterPro; IPR014797; CKK_domain.
DR InterPro; IPR011033; PRC_barrel-like_sf.
DR PANTHER; PTHR21595:SF1; CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 2; 1.
DR PANTHER; PTHR21595; UNCHARACTERIZED; 1.
DR Pfam; PF17095; CAMSAP_CC1; 1.
DR Pfam; PF11971; CAMSAP_CH; 1.
DR Pfam; PF08683; CAMSAP_CKK; 1.
DR SMART; SM01051; CAMSAP_CKK; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF50346; PRC-barrel domain; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS51508; CKK; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701, ECO:0000256|PROSITE-
KW ProRule:PRU00841}; Reference proteome {ECO:0000313|Proteomes:UP000245340}.
FT DOMAIN 222..335
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 1350..1484
FT /note="CKK"
FT /evidence="ECO:0000259|PROSITE:PS51508"
FT REGION 387..416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 600..640
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 666..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 813..883
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 926..1153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1192..1350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 762..789
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 889..926
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 401..416
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 600..622
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 671..700
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 713..729
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 813..839
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 858..882
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 926..1008
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1039..1078
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1080..1102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1103..1117
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1132..1153
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1192..1251
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1287..1303
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1331..1347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1490 AA; 168004 MW; A760CEFF96BE8D68 CRC64;
MGDAADPREM KKTFIVPAIK PFDHYDFSRA KIACNLAWLV AKAFGTENVP EELREPFYTD
QYDQEHIKPP VVNLLLSAEL YCRAGSLILK SDAAKPLLGH DAVIQALAQK GLYVTDQEKL
VTERDLHKKP IQMSAHLAMI DTLMMAYTVE MVSIEKVIAC AQQYSAFFQA TDLPYDIEDA
VMYWINKVNE HLKDIMEQEQ KLKEHHTVEA PGGQKSPSKW FWKLVPARYR KEQTLLKQLP
CIPLVENLLK DGTDGCALAA LIHFYCPGVV RLEDICLKET MSLADSLYNL QLIQEFCQEY
LNQCCHFTLE DMLYAASSIK SNYLVFMAEL FWWFEVVKPS FVQPRVVRPQ GAEPVNDMPS
IPVLNAAKTN ILDSSCSSDF TSSGEGAAFT HSHHLPSRHS RSQAHSSASG GIRRSSSMSY
VDGFIGTWPK EKRSSVHGVS FDISFDKENT VHRSTPNRGI TRSISNEGLT LNNNRVSKNI
RKNLSFKPVN GEEEAESIEE ELNIDSHSGL KSYTLLNTNE LNSNENIHYK LPNGALQNRV
LLDEFGNQIE TPSIEEALQI IHDTEKSPHT SQPDHIANGF FLHNQEMSIL NSNIKLNQSS
PDNITDTKGA LSPITDNTEV DTGIHVPSED IPETMDEDSS LRDYTVSLDS DMDDASKFLQ
DYDIRTSNPR EALSPCPSTV STKSQPGSSA SSSSGVKMTS FAEQKFRKLN HTDGKSSGSS
SQKTTPEGSE LNIPHVVAWG QIPEEAGLPQ GRDTTQLLAS EMVHLRMKLE EKRRAIEAQK
KKMEAAFTKQ RQKMGRTAFL TVVKKRGDGI SPLREEAAGA EDEKVYTDRA KEKDSQKANG
QRSKSLADLK ESMENPQAKW LKSPTTPIDP EKQWNLASPS EETLNEGEIL EYTKSIEKLN
SSLHFLQQEM QRLSLQQEML MQMREQQSWV ISPPQPSPQK QIRDFKPSRQ AGLSSASAPF
SSDAPRPTHP SPQSSNRKNT SFSVKNQRTP RPNELKITPL NRTLTPPRSV DSLPRLRRFS
PSQVPIQTRS FVCFGDDGEP QLKESKPKEE VKKEELESKG PVGQHVRNPE EKEIRPLEST
VSEVLSQPIT ETVRLTPNED QLNQPAEPPP KPVFPPAAPK NVNLIEVSLS DLKPPEKADV
SVEKYDGESD KEQFDDDQKV CCGFFFKDDQ KAENDMAMKR AALLEKRLRR EKETQLRKQQ
LEAEMEHKKE ETRRKTEEER QKKEDEKARR EFIRQEYMRR KQLKLMEDMD TVIKPRPQIA
KQKKQRPKSI HRDHIESPKT PIKGPPVSSL SLASLNTGDN ESVHSGKRTP RSESVEGFLS
PSRCGSRNGE KDWENASTTS SVASGTEYTG PKLYKEPSAK SNKHIIQNAL AHCCLAGKVN
EGQKKKILEE MEKSDANNFL ILFRDSGCQF RSLYTYCPET EEINKLTGIG PKSITKKMIE
GLYKYNSDRK QFSHIPAKTL SASVDAITIH SHLWQTKRPV TPKKLLPTKA
//
