ID A0A2U3VFM8_ODORO Unreviewed; 783 AA.
AC A0A2U3VFM8;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Protein VAC14 homolog {ECO:0000256|ARBA:ARBA00013840};
GN Name=VAC14 {ECO:0000313|RefSeq:XP_004393345.1};
OS Odobenus rosmarus divergens (Pacific walrus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC Odobenus.
OX NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004393345.1};
RN [1] {ECO:0000313|RefSeq:XP_004393345.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Microsome membrane
CC {ECO:0000256|ARBA:ARBA00004524}.
CC -!- SIMILARITY: Belongs to the VAC14 family.
CC {ECO:0000256|ARBA:ARBA00010225}.
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DR RefSeq; XP_004393345.1; XM_004393288.1.
DR AlphaFoldDB; A0A2U3VFM8; -.
DR STRING; 9708.A0A2U3VFM8; -.
DR GeneID; 101385443; -.
DR KEGG; oro:101385443; -.
DR CTD; 55697; -.
DR InParanoid; A0A2U3VFM8; -.
DR OrthoDB; 5481081at2759; -.
DR Proteomes; UP000245340; Unplaced.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0070772; C:PAS complex; IEA:InterPro.
DR GO; GO:0006661; P:phosphatidylinositol biosynthetic process; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026825; Vac14.
DR InterPro; IPR021841; VAC14_Fig4p-bd.
DR PANTHER; PTHR16023:SF0; PROTEIN VAC14 HOMOLOG; 1.
DR PANTHER; PTHR16023; TAX1 BINDING PROTEIN-RELATED; 1.
DR Pfam; PF12755; Vac14_Fab1_bd; 1.
DR Pfam; PF11916; Vac14_Fig4_bd; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022848};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Microsome {ECO:0000256|ARBA:ARBA00022848};
KW Reference proteome {ECO:0000313|Proteomes:UP000245340};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 543..721
FT /note="Vacuolar protein 14 C-terminal Fig4-binding"
FT /evidence="ECO:0000259|Pfam:PF11916"
FT REGION 331..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 472..495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 764..783
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 371..385
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 783 AA; 87946 MW; 537DA96A3120D6CC CRC64;
MNPEKDFAPL TPNIVRALND KLYEKRKVAA LEIEKLVREF VAQNNTVQIK HVIQTLSQEF
ALSQHPHSRK GGLIGLAACS IALGKDSGLY LKELIEPVLT CFNDADSRLR YYACEALYNI
VKVARGAVLP HFNVLFDGLS KLAADPDPNV KSGSELLDRL LKDIVTESNK FDLVGFIPLL
RERIYSNNQY ARQFIISWIL VLESVPDINL LDYLPEILDG LFQILGDNGK EIRKMCEVVL
GEFLKEIKKN PSSVKFAEMA NILVIHCQTT DDLIQLTAMC WMREFIQLAG RVMLPYSSGI
LTAVLPCLAY DDRKKSIKEV ANVCNQSLMK LVTPEDDEPD EPKPMAQRLA EPNPDDTPAK
QEGTAGGGPD GSCDSSFSSG SSVLTPASTE RAPVTLHLDG IVQVLNCHLS DMAIGMMTRI
AVLKWLYHLY IKTPRKMFRH TDSLFPILLQ TLSDESDEVI LKDLEVLAEI ASSPAGQTDD
PGPPDGPDLR VSHSELQVPT PGRANLLNTP GTKGLECSPS TPTMNSYFYK FMINLLKRFS
SERKLLEARG AFIIRQLCLL LNAENIFHSM ADILLQEEDL KFASTMVHTL NTILLTSTEL
FQLRNQLKDL KTLESQNLFC CLYRSWCHNP VTTVSLCFLT QNYRHAYDLI QKFGDLEVTV
DFLTEVDKLV QLIECPIFTY LRLQLLDVRN NPYLIKALYG LLMLLPQCSA FQLLSHRLQC
VPKPELLQAG DSPPAAPKSQ KADSPSIDYA ELLQHFEKVQ KKHLDARHQR SGRGDHLDRR
VVL
//
