ID A0A2U3VFY9_ODORO Unreviewed; 247 AA.
AC A0A2U3VFY9;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Membrane-associated progesterone receptor component 2 {ECO:0000313|RefSeq:XP_004393656.1};
GN Name=PGRMC2 {ECO:0000313|RefSeq:XP_004393656.1};
OS Odobenus rosmarus divergens (Pacific walrus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC Odobenus.
OX NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004393656.1};
RN [1] {ECO:0000313|RefSeq:XP_004393656.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the cytochrome b5 family. MAPR subfamily.
CC {ECO:0000256|ARBA:ARBA00038357}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_004393656.1; XM_004393599.2.
DR AlphaFoldDB; A0A2U3VFY9; -.
DR STRING; 9708.A0A2U3VFY9; -.
DR GeneID; 101364453; -.
DR KEGG; oro:101364453; -.
DR CTD; 10424; -.
DR InParanoid; A0A2U3VFY9; -.
DR OrthoDB; 148785at2759; -.
DR Proteomes; UP000245340; Unplaced.
DR Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR PANTHER; PTHR10281:SF24; MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT 2; 1.
DR PANTHER; PTHR10281; MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED; 1.
DR Pfam; PF00173; Cyt-b5; 1.
DR SMART; SM01117; Cyt-b5; 1.
DR SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
PE 3: Inferred from homology;
KW Receptor {ECO:0000313|RefSeq:XP_004393656.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000245340}.
FT DOMAIN 127..225
FT /note="Cytochrome b5 heme-binding"
FT /evidence="ECO:0000259|SMART:SM01117"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 31..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 226..247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 247 AA; 26231 MW; 2B62BBA1E205E2DE CRC64;
MGGVGRGVGE GRGRRGGGRR WRAVMAAGDG DVKLGTLGSG SESSSDGSSE SPSGAGAATE
GGGWAAAALA LLTGGGEMLL NVALVALVLL GAYRLWVRWG RRGLGAGAGA GEESPAASLP
RMKKRDFSLE QLRQYDGSRT PRILLAVNGK VFDVTKGSKF YGPAGPYGIF AGRDASRGLA
TFCLDKDALK DEYDDLSDLN AVQMESVREW EMQFKEKYDY VGRLLKPGEE PSEYTDEEDT
KDHNKQD
//
