ID A0A2U3VHT2_ODORO Unreviewed; 521 AA.
AC A0A2U3VHT2;
DT 18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT 18-JUL-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Tripartite motif-containing protein 65 isoform X1 {ECO:0000313|RefSeq:XP_004394377.1};
GN Name=TRIM65 {ECO:0000313|RefSeq:XP_004394377.1};
OS Odobenus rosmarus divergens (Pacific walrus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Odobenidae;
OC Odobenus.
OX NCBI_TaxID=9708 {ECO:0000313|Proteomes:UP000245340, ECO:0000313|RefSeq:XP_004394377.1};
RN [1] {ECO:0000313|RefSeq:XP_004394377.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_004394377.1; XM_004394320.2.
DR AlphaFoldDB; A0A2U3VHT2; -.
DR STRING; 9708.A0A2U3VHT2; -.
DR GeneID; 101381794; -.
DR KEGG; oro:101381794; -.
DR CTD; 201292; -.
DR InParanoid; A0A2U3VHT2; -.
DR OrthoDB; 828004at2759; -.
DR Proteomes; UP000245340; Unplaced.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR CDD; cd19835; Bbox2_TRIM65_C-IV; 1.
DR CDD; cd12896; SPRY_PRY_TRIM65; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR048222; TRIM65_SPRY_PRY.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF29; TRIPARTITE MOTIF-CONTAINING PROTEIN 65; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000245340};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 12..51
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 315..508
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 75..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 140..174
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 521 AA; 57667 MW; E1FC2439CFC57FD6 CRC64;
MATPPLEDEL TCSICLGLYL EPVTLLCGHN FCGACIRDWG DRYDKACPEC RKPFPDGAEL
RRNVALSAVL KAMRAGPAPA PGPDPARASG SAPGARCPRH GRPLDLFCRT EGRCICSACT
VNECRLHERA LLDAERRERE AQLRAMLEVS QQQATQAERQ LKELQRQRSQ IQSSACSLAS
VISSKFSCLL QALEMRQALA LRDIKVAETQ ALAQARDGEE RLQGHLEALA SYDRGVRDLL
EQLDDRAFLQ ESQLLVPPGP LGPLTSPQWD EDQQLAGLKE SLSQLCGLLL DEGGHPRAPA
EAADLGPVGA PGPLAPVPSP VCPLRRKLWQ NYRNLTFDPD SANRHLYLSR QDQQVKHRHK
PRDLAGPSSF ELWQVRCAQS FQNGRHYWEV HASNHSVTLG VAYPDLTRHR QGPHTDNIGR
GPSSWGLCVQ EDRAQAWHNG EAQLLPGVSG QLLGMDLDLA SGCLTFYSLE PKAQPLHTFH
AIFTRPLYPV FWLLEGRTLT LCHRPEAKLP PEPQEEASEP S
//
